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Mashup Score: 17Exploring the Neurobiology of Hearing: Winner of the 2023 Neuroscience Cover Competition - IBRO - 21 day(s) ago
With fine representations of neurons crucial for hearing – the bushy cells – the winner of the 2023 Neuroscience cover competition captures the beauty of these neurons and the natural changes that occur over time.
Source: ibro.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 1Identification of PS1/gamma-secretase and glutamate transporter GLT-1 interaction sites - 21 day(s) ago
The recently discovered interaction between Presenilin 1 (PS1), a catalytic subunit of γ-secretase responsible for generating amyloid-β peptides, and GLT-1, a major glutamate transporter in the brain (EAAT2), provides a mechanistic link between these two key factors involved in Alzheimer’s disease (AD) pathology. Modulating this interaction can be crucial to understand the consequence of such crosstalk in AD context and beyond. However, the interaction sites between these two proteins are unknown.
Source: www.jbc.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 20The cerebellum monitors errors and entrains executive networks - 25 day(s) ago
Frontal midline θ (Fmθ) activity occurs in medial prefrontal cortices (mPFC), when expected and actual outcomes conflict. Cerebellar forward models co…
Source: www.sciencedirect.comCategories: General Medicine News, NeurologyTweet
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Mashup Score: 5
This ALBA-IBRO webinar highlights concrete initiatives and programmes, primarily at the institutional level, aimed at closing the gender gap in global brain research.
Source: www.alba.networkCategories: General Medicine News, NeurologyTweet
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Mashup Score: 16Exploring the Neurobiology of Hearing: Winner of the 2023 Neuroscience Cover Competition - IBRO - 27 day(s) ago
With fine representations of neurons crucial for hearing – the bushy cells – the winner of the 2023 Neuroscience cover competition captures the beauty of these neurons and the natural changes that occur over time.
Source: ibro.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 2Biochemical and cellular characterization of the CISD3 protein: Molecular bases of cluster release and destabilizing effects of nitric oxide - 27 day(s) ago
The NEET proteins, an important family of iron-sulfur (Fe-S) proteins, have generated a strong interest due to their involvement in diverse diseases such as cancer, diabetes, and neurodegenerative disorders. Among the human NEET proteins, CISD3 has been the least studied, and its functional role is still largely unknown. We have investigated the biochemical features of CISD3 at the atomic and in cellulo levels upon challenge with different stress conditions i.e., iron deficiency, exposure to hydrogen peroxide, and nitric oxide.
Source: www.jbc.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 2ScienceDirect - 28 day(s) ago
Read the latest articles of Brain Organoid and Systems Neuroscience Journal at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature
Source: www.sciencedirect.comCategories: General Medicine News, NeurologyTweet
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Mashup Score: 16
Obesity is considered a global health problem, having the characteristics of a pandemic disease. According to the most robust studies, it is estimated that a total of 1.9 billion and 609 million adults are overweight or obese, respectively (WHO, 2017; Blüher, 2019). Although it has a multifactorial cause and several classifications, obesity is commonly the result of a positive energy balance, especially when it involves consumption of foods rich in carbohydrates, saturated and trans fats. This type of food (i.e.
Source: www.ibroneuroscience.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 2Activation of innate immune receptor TLR9 by mitochondrial DNA plays essential roles in the chemical long-term depression of hippocampal neurons - 29 day(s) ago
Synaptic plasticity is believed to be the cellular basis for experience-dependent learning and memory. Although long-term depression (LTD), a form of synaptic plasticity, is caused by the activity-dependent reduction of cell surface α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA)-type glutamate receptors (AMPA receptors) at postsynaptic sites, its regulation by neuronal activity is not completely understood. In this study, we showed that the inhibition of toll-like receptor-9 (TLR9), an innate immune receptor, suppresses N-methyl-d-aspartate (NMDA)-induced reduction of cell surface AMPA receptors in cultured hippocampal neurons.
Source: www.jbc.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 2
Addiction is characterized by continued drug use despite negative consequences. In an animal model, a subset of rats continues to self-administer coca…
Source: www.sciencedirect.comCategories: General Medicine News, NeurologyTweet
The prize for the best Neuroscience cover of 2023 goes to Drs. Ruili Xie, Meijian Wang, Chuangeng Zhang, and Shengyin Lin! Congratulations! Read the research behind the cover in an interview with Dr. Xie > https://t.co/J22Zw8Y76u @NeurosciIBRO @IBROorg https://t.co/e8M7ztDaNj