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Mashup Score: 2Exploring DESTINY: the Past, Present, and Future of Trastuzumab Deruxtecan - PubMed - 4 month(s) ago
T-DXd is a novel antibody-drug conjugate (ADC) composed of a humanized IgG1 monoclonal antibody against HER2 receptor bound to a potent topoisomerase I cytotoxin payload by a cleavable peptide linker. It has been shown to have robust preclinical activity in pretreated cancer cell lines, as well as m …
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 20Dementia in Women Using Estrogen-Only Therapy - 5 month(s) ago
This study examines the association between use of estrogen-only therapy for perimenopausal and menopausal women and risk of dementia.
Source: jamanetwork.comCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 31
Acquired ESR1 mutations in estrogen receptor-positive (ER+) metastatic breast cancer (mBC) drive treatment resistance and tumor progression; new treatment strategies are needed. Lasofoxifene, a next-generation, oral, endocrine therapy and tissue-specific ER antagonist, provided preclinical antitumor activity, alone or combined with a cyclin-dependent kinase 4/6 inhibitor (CDK4/6i) in ESR1-mutated mBC.
Source: www.annalsofoncology.orgCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 16
The Rhode Island Department of Transportation announced they will be closing the westbound side of the Washington Bridge.
Source: turnto10.comCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 16
The Rhode Island Department of Transportation announced they will be closing the westbound side of the Washington Bridge.
Source: turnto10.comCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 43Pregnancy After Breast Cancer in Young BRCA Carriers - 5 month(s) ago
This retrospective cohort study assesses the cumulative incidence of pregnancy after cancer and disease-free survival in BRCA carriers diagnosed with invasive breast cancer at age 40 years or younger.
Source: jamanetwork.comCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 39Pregnancy After Breast Cancer in Young BRCA Carriers - 5 month(s) ago
This retrospective cohort study assesses the cumulative incidence of pregnancy after cancer and disease-free survival in BRCA carriers diagnosed with invasive breast cancer at age 40 years or younger.
Source: jamanetwork.comCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 39Pregnancy After Breast Cancer in Young BRCA Carriers - 5 month(s) ago
This retrospective cohort study assesses the cumulative incidence of pregnancy after cancer and disease-free survival in BRCA carriers diagnosed with invasive breast cancer at age 40 years or younger.
Source: jamanetwork.comCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 39Pregnancy After Breast Cancer in Young BRCA Carriers - 5 month(s) ago
This retrospective cohort study assesses the cumulative incidence of pregnancy after cancer and disease-free survival in BRCA carriers diagnosed with invasive breast cancer at age 40 years or younger.
Source: jamanetwork.comCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 15Podcast: Breast Cancer Treatment Options After CDK4/6 Inhibitors - 5 month(s) ago
Listen to Dr. Stephanie Graff explain the breast cancer treatments available after one CDK4/6 inhibitor has stopped working.
Source: www.breastcancer.orgCategories: General Medicine News, Hem/OncsTweet
RT @AzkaAliMD: Check out our recent review on what’s current and next for T- DXd https://t.co/YMvQVsW8sH @DrSGraff @ClevelandClinic @CleCli…