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Mashup Score: 2SPTLC3 Is Essential for Complex I Activity and Contributes to Ischemic Cardiomyopathy - 6 day(s) ago
BACKGROUND: Dysregulated metabolism of bioactive sphingolipids, including ceramides and sphingosine-1-phosphate, has been implicated in cardiovascular disease, although the specific species, disease
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Mashup Score: 4Piezo1-Mediated Neurogenic Inflammatory Cascade Exacerbates Ventricular Remodeling After Myocardial Infarction - 6 day(s) ago
BACKGROUND: Heart failure is associated with a high rate of mortality and morbidity, and ventricular remodeling invariably precedes heart failure. Ventricular remodeling is fundamentally driven by me
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Mashup Score: 3
BACKGROUND: Among patients with pulmonary arterial hypertension (PAH), acute vasoreactivity testing during right heart catheterization may identify acute vasoresponders, for whom treatment with high-
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Mashup Score: 50
Aim The “2024 AHA/ACC/AMSSM/HRS/PACES/SCMR Guideline for the Management of Hypertrophic Cardiomyopathy” provides recommendations to guide clinicians in the management of patients with hypertrophic ca
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Mashup Score: 20
BACKGROUND: Heart failure triggers a shift in myocardial metabolic substrate utilization, favoring the ketone body 3-hydroxybutyrate as energy source. We hypothesized that 14-day treatment with keton
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Mashup Score: 20
BACKGROUND: Heart failure triggers a shift in myocardial metabolic substrate utilization, favoring the ketone body 3-hydroxybutyrate as energy source. We hypothesized that 14-day treatment with keton
Source: www.ahajournals.orgCategories: General Medicine News, Cardiology News and JournTweet
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Mashup Score: 50
Aim The “2024 AHA/ACC/AMSSM/HRS/PACES/SCMR Guideline for the Management of Hypertrophic Cardiomyopathy” provides recommendations to guide clinicians in the management of patients with hypertrophic ca
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Mashup Score: 41Reduced Ejection Fraction in Elite Endurance Athletes: Clinical and Genetic Overlap With Dilated Cardiomyopathy - 7 day(s) ago
BACKGROUND: Exercise-induced cardiac remodeling can be profound, resulting in clinical overlap with dilated cardiomyopathy, yet the significance of reduced ejection fraction (EF) in athletes is uncle
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Mashup Score: 5
Department of Anesthesiology and Intensive Care Medicine, University Hospital of Cologne, Germany (J.S.). University of Cologne, Faculty of Medicine and University Hospital Cologne, Clinic III for Internal Medicine, Cologne, Germany (J.-N.H.). Department of Internal Medicine III, Division of Cardiology, Pneumology, Angiology, and Intensive Care, University of Cologne, Germany (J-N.H., J.J.). Institute of Experimental Epileptology and Cognition Research (D.A.), University of Bonn Medical Center, Germany.
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Mashup Score: 20Unraveling the Unsolved Mysteries of the Athletic Heart - 7 day(s) ago
Division of Cardiology, Department of Medicine, University of Colorado, Aurora (W.K.C.). Clinical Translational Research Center, University of Colorado Anschutz Medical Center, Aurora, CO (W.K.C.). Correspondence to: Benjamin D. Levine, MD, Institute for Exercise and Environmental Medicine, 7232 Greenville Ave, Dallas TX 75231. Email Division of Cardiology, University of Texas Southwestern Medical Center, Dallas (B.D.L.). Texas Health Presbyterian Hospital, Institute for Exercise and Environmental
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#OriginalResearch: Depletion of SPTLC3 dependent sphingolipid biosynthesis is protective in ischemic cardiomyopthy via inactivation of complex https://t.co/WDu2Z0iPWC