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Mashup Score: 26Sinonasal DLBCL: molecular profiling identifies subtypes with distinctive prognosis and targetable genetic features - 6 day(s) ago
ABC and GCB subtype sinonasal DLBCL are geno- and phenotypically distinct entities, exhibiting a contrasting disease course and prognosis.ABC subtype sinon
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Mashup Score: 0A molecular circuit linking the BCR to the NAD biosynthetic enzyme NAMPT is an actionable target in Richter syndrome - 6 day(s) ago
BCR cross-linking activates a positive feedback loop including NAMPT and sirtuins and converging on AKT activation.PI3Kγ/δ and NAMPT inhibitors synergize i
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Mashup Score: 8Tyrosine kinase inhibitor resistance in de novo BCR::ABL1–positive BCP-ALL beyond kinase domain mutations - 6 day(s) ago
Imatinib resistance at diagnosis was higher in cells of patients who relapsed vs those in remission after imatinib and chemotherapy.Low levels of BCR::ABL1
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Mashup Score: 11Comparison of antibody-based immunotherapeutics for malignant hematological disease in an experimental murine model - 7 day(s) ago
New mouse model allows for side-by-side comparison of antitumor activity and side effects of immunotherapeutics targeting the same epitope.Immunotherapies
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Mashup Score: 2Human Fc gamma receptor IIIA blockade inhibits platelet destruction in a humanized murine model of ITP - 7 day(s) ago
Human FcγRIII monovalent blocking as a 1-armed antibody or albumin fusion protein are effective in a humanized model of ITP.The monovalent albumin fusion p
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Mashup Score: 56Applying the EHA/EBMT grading for ICAHT after CAR-T: comparative incidence and association with infections and mortality - 7 day(s) ago
The novel EHA/EBMT grading of ICAHT closely reflects the extent of hematological toxicity following BCMA- and CD19-directed CAR-T therapy.Severe ICAHT was
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Mashup Score: 3Immunophenotypic predictors of influenza vaccine immunogenicity in pediatric hematopoietic cell transplant recipients - 8 day(s) ago
Baseline numbers of certain immune cells predicted influenza vaccine immunogenicity in pediatric HCT recipients.Immune reconstitution profiles could inform
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Mashup Score: 9Incidence and risk factors of pain crisis after hematopoietic cell transplantation for sickle cell disease - 8 day(s) ago
Recurrence of VOC requiring hospitalization or treatment occurs in 8.7% of patients after HCT with stable donor engraftment in SCD.GF, age at HCT, prior hi
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Mashup Score: 29Flares of acute graft-versus-host disease: a Mount Sinai Acute GVHD International Consortium analysis - 8 day(s) ago
After initial clinical response, flares of acute GVHD are common and associated with higher NRM.MAGIC biomarkers at first CR/VGPR can predict GVHD flares.
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Mashup Score: 4Human Fc gamma receptor IIIA blockade inhibits platelet destruction in a humanized murine model of ITP - 10 day(s) ago
Human FcγRIII monovalent blocking as a 1-armed antibody or albumin fusion protein are effective in a humanized model of ITP.The monovalent albumin fusion p
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ABC subtype sinonasal DLBCL is part of a superordinate family of MCD lymphomas, presenting at immune-privileged and other extranodal sites. https://t.co/bKQXdJMb33 #lymphoidneoplasia https://t.co/ZjP3h2s9BN