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Mashup Score: 6Specificity of CRISPR-Cas9 Editing in Exagamglogene Autotemcel | NEJM - 45 minute(s) ago
The autologous cellular therapy exagamglogene autotemcel is generated by editing an erythroid-specific enhancer of BCL11A. Could another site be edited unintentionally? This study gauged the likeli…
Source: www.nejm.orgCategories: General Medicine News, General HCPsTweet
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Mashup Score: 5Measuring Exhaled Nitric Oxide When Diagnosing and Managing Asthma - 45 minute(s) ago
Cleveland Clinic pulmonologists address the role of measuring exhaled nitric oxide in the diagnosis and management of asthma and provide guidance for its appropriate use
Source: consultqd.clevelandclinic.orgCategories: General Medicine News, General HCPsTweet
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Mashup Score: 1James Blyth: The Scots engineer who pioneered the wind turbine - 47 minute(s) ago
When James Blyth created his first wind turbine, villagers dismissed it as the “work of the devil”.
Source: www.bbc.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 3Cyber expert urges against 'panic' over NHS data leak - 53 minute(s) ago
Thousands of patient records from NHS Dumfries and Galloway have been posted online by a ransomware group.
Source: www.bbc.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 2Polyarteritis Nodosa | NEJM - 56 minute(s) ago
A 62-year-old man presented with a 1-month history of muscle aches in the legs and weight loss. Abdominal angiography revealed aneurysms and irregularity of the walls of multiple arteries.
Source: www.nejm.orgCategories: General Medicine News, General HCPsTweet
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Mashup Score: 0Do Phytosterols and Phytostanols Help Lower Cholesterol? - 1 hour(s) ago
Phytosterols and phytostanols are like plant versions of cholesterol. But unlike animal-based cholesterols, theyโre good for your heart.
Source: www.henryford.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 04 ways to transform customer service in enterprise IT - 1 hour(s) ago
Don’t underestimate the importance of exceptional customer service for your enterprise IT customers. These four strategies can help you stand out
Source: enterprisersproject.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 79Physiological Integration of Taste and Metabolism | NEJM - 1 hour(s) ago
Much of what we learned in school about how we taste is wrong. Progress in understanding how taste works is providing insights that may help in the management of obesity, diabetes, and other illnesses.
Source: www.nejm.orgCategories: General Medicine News, General HCPsTweet
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Mashup Score: 6Risk assessment in pT1 colorectal cancer - 1 hour(s) ago
Colorectal cancer (CRC) is a common malignancy worldwide and tumour stage is closely related to clinical outcome. A small but significant proportion of submucosal-invasive (ie, pT1) CRC are associated with regional lymph node metastases (LNM) and a worse prognosis. The likelihood of LNM in pT1 CRC needs to be balanced against the operative risk and costs of surgical resection when determining the best patient management. A wide range of histopathological and clinical factors may affect LNM risk in this setting. This script provides a comprehensive overview of the tumour and patient-associated features that have been linked to LNM risk in pT1 CRC. Some of the features are well established within the literature and are included in published guidelines, while others are novel and emerging in nature. Odds ratios for LNM that are associated with key predictive features are provided where appropriate, and published models developed as an aid to the calculation of LNM risk are discussed.
Source: jcp.bmj.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 21
In patients with immune thrombotic thrombocytopenic purpura (iTTP), autoantibodies against the metalloprotease ADAMTS13 lead to catastrophic microvascular thrombosis. However, the potential benefit…
Source: www.nejm.orgCategories: General Medicine News, General HCPsTweet
The autologous cellular therapy exagamglogene autotemcel is generated by editing an erythroid-specific enhancer of BCL11A. Could another site be edited unintentionally? This study gauged the likelihood of off-target editing. Read the full correspondence: https://t.co/jX714YVL3A https://t.co/NT58JhlbOM