Treating DCIS: To Escalate or De-escalate?
There is much debate about the necessity of treating women with ductal carcinoma in situ (DCIS) with surgery or radiotherapy. 1,2 It is disconcerting to many that patients with DCIS are treated in the same way as are women with early-stage invasive breast cancer. Many patients with DCIS have bilateral mastectomies. 2 Much effort is being expended to identify women at sufficiently low risk who might avoid surgery and/or radiotherapy. 3-9 In a recent paper from the UK, Mannu et al followed women with DCIS