The new NCCN guidelines for immunotherapy-related toxicities – OncoDaily
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Dissection of Progressive Disease Patterns for a Modified Classification for Immunotherapy
This study examines a modified progressive disease classification and its association with postprogression survival in patients treated with atezolizumab across various solid tumors.
PSCA-targeted BPX-601 CAR T cells with pharmacological activation by rimiducid in metastatic pancreatic and prostate cancer: a phase 1 dose escalation trial
Nature Communications – The success of CAR T cell therapies against solid tumors remains limited. Here the authors report the results of a phase 1…
Immune deficiency in uremia: interleukin-2 production and responsiveness and interleukin-2 receptor expression and release – PubMed
We have studied the role of interleukin-2 (IL-2) and its receptors in the impaired in vitro lymphocyte response characteristic of hemodialysis patients treated by means…
Targeting the Opioid Pathway for Uremic Pruritus: A Systematic Review and Meta-analysis
Patients undergoing hemodialysis or peritoneal dialysis often experience pruritus which is associated with morbidity and mortality. One proposed treatment approach is to target the opioid…
Disappearance of uraemic pruritus after lowering dialysate magnesium concentration
Official websites use .gov A.gov website belongs to an official government organization in the United States. Secure .gov websites use HTTPS A lock () or…
Increased plasma histamine levels in uraemic pruritus – PubMed
1. We determined plasma levels of histamine in uraemic patients and examined their correlation with the presence of pruritus. 2. In 27 patients with chronic…
Pruritus in hemodialysis patients
Pruritus is one of the most bothersome symptoms in patients on maintenance hemodialysis (HD), however little progress is seen in our understanding of its pathogenesis.…