Nature Reviews Rheumatology – This Review provides an overview of the pathogenesis, classification and diagnosis of and treatment strategies for adult and paediatric rheumatology patients with…
Nature Reviews Cardiology – In this Review, Borén and colleagues present insights into the role of apolipoprotein B-containing lipoproteins in atherogenesis, with an emphasis on…
Nature Medicine – Results from this single-arm cohort of the BFAST trial showed that the clinical efficacy of entrectinib in patients with ROS1-positive NSCLC, selected…
Nature Medicine – In the observational ZERO Childhood Cancer Precision Medicine Program PRecISion Medicine for Children with Cancer (PRISM) trial, children with high-risk cancer were…
Nature Medicine – In a cohort of 281 children with diagnosed or suspected cancer presenting to the NHS, implementing routine whole-genome sequencing provided clinical benefit…
Objectives Little is known on the mechanisms necessary to maintain the physiological adult human skin integrity. This study aims to quantitatively describe anatomical changes in…
Nature Biotechnology – A language model predicts the effects of genetic variants in the human genome.
Nature Reviews Drug Discovery – The FDA approved 50 new therapeutics in 2024, with green lights for a novel schizophrenia drug, a first NASH medicine…
Nature – Convergent mutations in hotspots of the SARS-CoV-2 Omicron receptor-binding domain can cause immune evasion and maintain sufficient ACE2-binding capability.
Nature Communications – Using clinico-genomic data from 78,287 cancer patients, this study identifies genomic alterations linked to survival outcomes, advancing precision oncology by predicting…
Nature – DNA damage caused by a high-fat diet can increase the risk of tumour formation in the liver.
