The deacetylase SIRT6 reduces amyloid pathology and supports cognition in mice by reducing the stability of APP in neurons
The enzyme SIRT6 restrains neurotoxic amyloid production by promoting the degradation of its precursor.
The enzyme SIRT6 restrains neurotoxic amyloid production by promoting the degradation of its precursor.
Imaging-guided biodegradable microrobots can efficiently navigate biofluids for days, enhancing drug delivery efficiency.
“I didn’t want to write a proposal tailored to avoiding criticism,” this Ph.D. student writes
The pathway that activates AKT3 to drive epithelial-to-mesenchymal transition in pancreatic cancer is revealed.
Company found signs its shots made some infected kids sicker than expected, casting a new shadow over the previously troubled RSV vaccine field
Recent marine heatwaves have had pervasive effects on marine ecosystems, from declines in primary production to die-offs of top predators. Seabird mortalities are often observed…
Targeting a cell stress response is synthetic lethal with loss of p53 in prostate cancer cells.
Several leaders of a multinational effort expanding access to essential lab materials discuss its impact and a major funding boost
Structural analysis reveals species-specific differences in how the antibody IgE binds to its receptor FcεRI.
A brace of new studies probes benefits and risks for an understudied group
Acute oral metformin administration lowers blood glucose levels by targeting mitochondrial complex I.