Tethered | NEJM
When a bright young adult patient who had been planning his future moves back home to help his sick mother, his own emerging health problems are hard to interpret — until it’s too late.
When a bright young adult patient who had been planning his future moves back home to help his sick mother, his own emerging health problems are hard to interpret — until it’s too late.
Whether surgical axillary staging as part of breast-conserving therapy can be omitted without compromising survival has remained unclear. In this prospective, randomized, noninferiority trial, we…
This randomized noninferiority trial assesses the effect of a strategy of active monitoring vs guideline-concordant care on 2-year risk of ipsilateral invasive breast cancer among…
A December 2022 law introduced a new expedited withdrawal process for accelerated approvals. The first approval withdrawn with this pathway was that of melphalan flufenamide.
Audio Interview from the New England Journal of Medicine — Interview with Bindu Kanapuru on the FDA’s new expedited withdrawal procedure for accelerated approvals.
The role of axillary surgery in the management of breast cancer has changed. Sentinel-lymph-node biopsy is used to identify nodal metastases, but recognition of the…
Whether surgical axillary staging as part of breast-conserving therapy can be omitted without compromising survival has remained unclear. In this prospective, randomized, noninferiority trial, we…
Transthyretin amyloidosis with cardiomyopathy (ATTR-CM) is a progressive, often fatal disease. Nexiguran ziclumeran (nex-z) is an investigational therapy based on CRISPR-Cas9 (clustered regularly i…
Standard multidrug therapy for leprosy may be associated with severe side effects, which add to the stigma and discrimination that affect persons with the disease.…
The benefit of percutaneous coronary intervention (PCI) in patients with stable coronary artery disease and severe aortic stenosis who are undergoing transcatheter aortic-valve implantation (TAVI)…
Roughly 6 in 10 insured adults experience problems when they use their insurance, including insurers refusing to pay for care.