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Mashup Score: 1
Background Timely administration of antibiotics is one of the most important interventions in reducing mortality in sepsis. However, administering antibiotics within a strict time threshold in all patients suspected with sepsis will require huge amount of effort and resources and may increase the risk of unintentional exposure to broad-spectrum antibiotics in patients without infection with its…
Source: BioMed CentralCategories: Critical Care, Latest HeadlinesTweet
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Mashup Score: 1Hyperoxemia in postsurgical sepsis/septic shock patients is associated with reduced mortality - Critical Care - 2 year(s) ago
Background Despite growing interest in treatment strategies that limit oxygen exposure in ICU patients, no studies have compared conservative oxygen with standard oxygen in postsurgical patients with sepsis/septic shock, although there are indications that it may improve outcomes. It has been proven that high partial pressure of oxygen in arterial blood (PaO2) reduces the rate of surgical-wound…
Source: BioMed CentralCategories: Critical Care, Latest HeadlinesTweet-
#CritCare #OpenAccess #PaO2 & risk of death in patients with #sepsis/#septic_shock after major #surgery https://t.co/8rY9yoeOTG @jlvincen @ISICEM #FOAMed #FOAMcc #BMC #ICU #Hyperoxemia #infection https://t.co/gb5Ikeczsy
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Mashup Score: 0Biomarkers for sepsis: more than just fever and leukocytosis—a narrative review - Critical Care - 2 year(s) ago
A biomarker describes a measurable indicator of a patient’s clinical condition that can be measured accurately and reproducibly. Biomarkers offer utility for diagnosis, prognosis, early disease recognition, risk stratification, appropriate treatment (theranostics), and trial enrichment for patients with sepsis or suspected sepsis. In this narrative review, we aim to answer the question, “Do…
Source: BioMed CentralCategories: Critical Care, Latest HeadlinesTweet-
#CritCare #OpenAccess Do #biomarkers in patients with #sepsis predict #mortality, #MODS, or #organ_dysfunction? https://t.co/kIKuHEfnCD @jlvincen @ISICEM #FOAMed #FOAMcc #BMC #ICU #septic_shock #encephalopathy #inflammation https://t.co/BscI6BOAjJ
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Mashup Score: 7Vitamin C for ≥ 5 days is associated with decreased hospital mortality in sepsis subgroups: a nationwide cohort study - Critical Care - 2 year(s) ago
Background Previous randomized trials of vitamin C, hydrocortisone, and thiamine on sepsis were limited by short-term vitamin C administration, heterogeneous populations, and the failure to evaluate each component’s effect. The purpose of this study was to determine whether vitamin C alone for ≥ 5 days or in combination with corticosteroids and/or thiamine was associated with decreased mortality…
Source: BioMed CentralCategories: Critical Care, Latest HeadlinesTweet-
#CritCare #OpenAccess Intravenous #vitaminC of ≥ 5 days is associated with reduced hospital and 90-day #mortality in #septic_patients https://t.co/lgKfWYEMqD @jlvincen @ISICEM #FOAMed #FOAMcc #BMC #ICU #sepsis #Septic_shock #Steroids #Thiamine #Ascorbic_acid https://t.co/OAJ8zZvwaO
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Mashup Score: 1
Research Letter Open Access Published: 18 November 2021 Critical…
Source: Critical CareCategories: Critical Care, Latest HeadlinesTweet-
#CritCare #OpenAccess Is #septic_shock associated with #telomere attrition? https://t.co/HZva3fbpOv @jlvincen @ISICEM #FOAMed #FOAMcc #BMC #ageing #inflammation #chromosome #sepsis #organ_failure https://t.co/3EbMB0LUm5
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Mashup Score: 30Norepinephrine potentiates the efficacy of volume expansion on mean systemic pressure in septic shock - Critical Care - 3 year(s) ago
Background Through venous contraction, norepinephrine (NE) increases stressed blood volume and mean systemic pressure (Pms) and exerts a “fluid-like” effect. When both fluid and NE are administered, Pms may not only result from the sum of the effects of both drugs. Indeed, norepinephrine may enhance the effects of volume expansion: because fluid dilutes into a more constricted, smaller, venous…
Source: Critical CareCategories: Latest Headlines, PediatricsTweet-
RT @Crit_Care: #CritCare #OpenAccess https://t.co/GnyaDwUW6y The #haemodynamic effect of #norepinephrine during #septic_shock #FOAMed #FO…
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Mashup Score: 2Norepinephrine potentiates the efficacy of volume expansion on mean systemic pressure in septic shock - Critical Care - 3 year(s) ago
Background Through venous contraction, norepinephrine (NE) increases stressed blood volume and mean systemic pressure (Pms) and exerts a “fluid-like” effect. When both fluid and NE are administered, Pms may not only result from the sum of the effects of both drugs. Indeed, norepinephrine may enhance the effects of volume expansion: because fluid dilutes into a more constricted, smaller, venous…
Source: Critical CareCategories: Critical Care, Latest HeadlinesTweet-
#CritCare #OpenAccess https://t.co/GnyaDwUW6y The #haemodynamic effect of #norepinephrine during #septic_shock #FOAMed #FOAMcc #BMC #ICU #IntensiveCare #Pms #leg_rising #fluid @jlvincen @ISICEM @of_aic https://t.co/C0EZuYdH9e
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Mashup Score: 2
Background While recommended by international societal guidelines in the paediatric population, the use of venoarterial extracorporeal membrane oxygenation (VA ECMO) as mechanical circulatory support for refractory septic shock in adults is controversial. We aimed to characterise the outcomes of adults with septic shock requiring VA ECMO, and identify factors associated with survival. Methods We…
Source: Critical CareCategories: Critical Care, Latest HeadlinesTweet-
#CritCare #OA #VA_ECMO for refractory #septic_shock: pros & cons https://t.co/DqzkkUpF8D #FOAMed #FOAMcc #BMC @ ISICEM @jlvincen #venoarterial #ECMO #sepsis #infection #cardiomyopathy https://t.co/PBX5w2o9Hs
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Mashup Score: 1Individualized resuscitation strategy for septic shock formalized by finite mixture modeling and dynamic treatment regimen - Critical Care - 3 year(s) ago
Background Septic shock comprises a heterogeneous population, and individualized resuscitation strategy is of vital importance. The study aimed to identify subclasses of septic shock with non-supervised learning algorithms, so as to tailor resuscitation strategy for each class. Methods Patients with septic shock in 25 tertiary care teaching hospitals in China from January 2016 to December 2017…
Source: Critical CareCategories: Critical Care, Latest HeadlinesTweet-
#CritCare #OA Tailoring a #resuscitation strategy for #septic_shock https://t.co/zvmeGolPAz #FOAMed #FOAMcc #BMC @ ISICEM @jlvincen #sepsis #fluid #infection https://t.co/DxlcBajOwY
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Mashup Score: 0Comparison of culture-negative and culture-positive sepsis or septic shock: a systematic review and meta-analysis - 3 year(s) ago
Background Mortality and other clinical outcomes between culture-negative and culture-positive septic patients have been documented inconsistently and are very controversial. A systematic review and meta-analysis was performed to compare the clinical outcomes of culture-negative and culture-positive sepsis or septic shock. Methods We searched the PubMed, Cochrane and Embase databases for studies…
Source: Critical CareCategories: Critical Care, Latest HeadlinesTweet-
#CritCare #OA Clinical #outcomes of #culture_negative vs #culture_positive #sepsis or #septic_shock https://t.co/2ub6NcxpGp #FOAMed #FOAMcc #BMC #ICU #Meta_analysis #review #Intensive_care @ISICEM @jlvincen https://t.co/xHOgOhRRHu
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#CritCare #OpenAccess Timely administration of #antibiotics is a key component in the early treatment of #sepsis. Is it always safe? https://t.co/dlrIjKjXir @jlvincen @ISICEM #FOAMed #FOAMcc #BMC #ICU #mortality #septic_shock #infection https://t.co/FkxCf9Vzd6