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    • Mashup Score: 1
      Selinexor Prolongs Progression-Free Survival in Recurrent... : Oncology Times - 2 year(s) ago

      An abstract is unavailable.

      Source: journals.lww.com
      Categories: Hem/Onc News and Journals, Latest Headlines
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      • Profile photo of 	OncologyTimes
        OncologyTimes

        Results of the Phase III study showed a substantial increase in PFS among #endometrialcancer patients in the TP53 WT subgroup receiving #selinexor (median 27.4 months) versus those receiving placebo (median 5.2 months). https://t.co/awq0VdtKyB #CancerResearch https://t.co/MoLiatoUsr

    • Mashup Score: 0
      Phase 3 Trial of Selinexor and Ruxolitinib Starts in JAKi-Naive Myelofibrosis - 2 year(s) ago

      Following promising phase 1 study results, the combination of selinexor and ruxolitinib is being evaluated in a phase 3 trial in patients with myelofibrosis.

      Source: Targeted Oncology
      Categories: Hem/Onc News and Journals, Latest Headlines
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      • Profile photo of 	TargetedOnc
        TargetedOnc

        A phase 3 clinical trial is assessing the efficacy and safety of #selinexor + #ruxolitinib in JAKi-naïve patients with #myelofibrosis. #mpnsm https://t.co/yTg1kjxV6a

    • Mashup Score: 1
      Managing Adverse Events With Selinexor in R/R Multiple Myeloma - 2 year(s) ago

      During a Targeted Oncology™ Case-Based Roundtable™ event, Sumit Madan, MD, discussed with participants what challenges they face using selinexor in patients with relapsed/refractory multiple myeloma. This is the second of 2 articles based on this event.

      Source: Targeted Oncology
      Categories: Hem/Onc News and Journals, Latest Headlines
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      • Profile photo of 	TargetedOnc
        TargetedOnc

        Sumit Madan, MD, discussed challenges when using #selinexor in patients with relapsed/refractory multiple myeloma. #mmsm | @MDAndersonNews https://t.co/H4yD7FdENW

    • Mashup Score: 0
      QW Selinexor 60 mg Plus Ruxolitinib Elicits Lasting Responses in Myelofibrosis - 2 year(s) ago

      Researchers are backing further investigation of 60 mg selinexor plus ruxolitinib based on positive phase 1/2 findings presented at the AACR Annual Meeting 2023.

      Source: Targeted Oncology
      Categories: Hem/Onc News and Journals, Latest Headlines
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      • Profile photo of 	TargetedOnc
        TargetedOnc

        Once-weekly #selinexor 60 mg + #ruxolitinib achieved rapid and deep spleen responses that were sustained and robust symptom improvements in patients with treatment-naïve #myelofibrosis. #AACR2023 #mpnsm | @cityofhope https://t.co/dF1zDtwcQ6

    • Mashup Score: 0
      Combination Ruxolitinib and Selinexor for the Treatment of Naïve Myelofibrosis - 2 year(s) ago

      Srdan Verstovsek, MD, reviews data presented at ASH 2022 on combination ruxolitinib and selinexor for the frontline treatment of myelofibrosis.

      Source: Targeted Oncology
      Categories: Hem/Onc News and Journals, Latest Headlines
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      • Profile photo of 	TargetedOnc
        TargetedOnc

        Srdan Verstovsek, MD, reviews data presented at ASH 2022 on combination #ruxolitinib and #selinexor for the frontline treatment of #myelofibrosis. #mpnsm | @MDAndersonNews https://t.co/kRlYhgBxPS

    • Mashup Score: 1
      Mechanism of Action of Selinexor and its Role in Multiple Myeloma - 2 year(s) ago

      Dr Joshua Richter describes the mechanism of action of XPO1 inhibitor selinexor and its use in treating multiple myeloma.

      Source: Targeted Oncology
      Categories: Hem/Onc News and Journals, Latest Headlines
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      • Profile photo of 	TargetedOnc
        TargetedOnc

        Listen to Joshua Richter, MD, describe the mechanism of action of XPO1 inhibitor #selinexor and its use in treating #multiplemyeloma. #mmsm @TischCancer @IcahnMountSinai @JoshuaRichterMD https://t.co/zqjLZwGt8Y

    • Mashup Score: 0
      Forsberg Explains How Selinexor Fits Into Sequencing Therapies in R/R Multiple Myeloma - 3 year(s) ago

      During a Targeted Oncology case-based roundtable event, Peter Forsberg, MD, discussed data from several trials of selinexor in patients with relapsed/refractory multiple myeloma.

      Source: Targeted Oncology
      Categories: Hem/Onc News and Journals, Latest Headlines
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      • Profile photo of 	TargetedOnc
        TargetedOnc

        During a Targeted Oncology case-based roundtable event, Peter Forsberg, MD, discussed data from several trials of #selinexor in patients with relapsed/refractory #multiplemyeloma. #mmsm | @CUCancerCenter @uchealth @ForsbergMD https://t.co/3fYT1zDjew https://t.co/CfPjVOTuue

    • Mashup Score: 1
      Between The Lines: Once Weekly Selinexor, Carfilzomib & Dexamethasone in Carfilzomib Non-Refractory Multiple Myeloma Patients - 3 year(s) ago

      Dr. Joseph Mikhael and Dr. Hakan Kaya review key efficacy and safety data for the combination of Selinexor, Carfilzomib and Dexamethasone in R/R MM and discuss optimal dosing and adverse event management strategies for selinexor.

      Source: Cancer Network
      Categories: Hem/Onc News and Journals, Latest Headlines
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      • Profile photo of 	CancerNetwrk
        CancerNetwrk

        Joseph Mikhael, MD, and Hakan Kaya, MD, review key efficacy and safety data for the combination of XRd in R/R multiple myeloma and discuss optimal dosing and adverse event management strategies for #selinexor. #mmsm | @jmikhaelmd https://t.co/zc5ugzR2V4

    • Mashup Score: 3
      Between The Lines: Guidelines for Use and Dosing of Selinexor in Multiple Myeloma - 3 year(s) ago

      Dr Joshua Richter and Dr Peter Forsberg review key trial data and dosing strategies for selinexor based combinations.

      Source: Cancer Network
      Categories: Hem/Onc News and Journals, Latest Headlines
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      • Profile photo of 	CancerNetwrk
        CancerNetwrk

        Joshua Richter, MD, and Peter Forsberg, MD, review key trial data and dosing strategies for selinexor-based combinations. #mmsm #selinexor | @JoshuaRichterMD @ForsbergMD https://t.co/9ffjkruKt2

    • Mashup Score: 3
      Selinexor: Clinical Pearls for Current and Future Use in R/R MM - 3 year(s) ago

      Dr Joseph Mikhael and Dr Hakan Kaya provide advice for community oncologists who use selinexor and discuss the future of selinexor in patients with R/R MM.

      Source: Cancer Network
      Categories: Hem/Onc News and Journals, Latest Headlines
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      • Profile photo of 	CancerNetwrk
        CancerNetwrk

        Dr Joseph Mikhael and Dr Hakan Kaya provide advice for community oncologists who use selinexor and discuss the future of selinexor in patients with R/R MM. #mmsm #selinexor | @jmikhaelmd https://t.co/9JIEFrRK0X

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