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Mashup Score: 120
Purpose of ReviewLack of consistent data and guidance have led to variations between clinicians in the management of pregnancy in women with multiple sclerosis (MS). Pregnant and/or lactating women are often excluded from clinical trials conducted in MS, …
Source: www.neurology.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 57
Background and ObjectivesPatients with pediatric-onset multiple sclerosis (POMS) typically experience higher levels of inflammation with more frequent relapses, and though patients with POMS usually recover from relapses better than adults, patients with …
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Mashup Score: 22Single-Cell Multi-Omics Map of Cell Type–Specific Mechanistic Drivers of Multiple Sclerosis Lesions | Neurology Neuroimmunology & Neuroinflammation - 1 month(s) ago
Background and ObjectivesIn progressive multiple sclerosis (MS), compartmentalized inflammation plays a pivotal role in the complex pathology of tissue damage. The interplay between epigenetic regulation, transcriptional modifications, and location-…
Source: www.neurology.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 26
Background and ObjectivesPeople with multiple sclerosis (MS) have a dysregulated circulating metabolome, but the metabolome of MS brain lesions has not been studied. The aims of this study were to identify differences in the brain tissue metabolome in MS …
Source: www.neurology.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 34Outcome Reporting Bias in Clinical Trials Researching Disease-Modifying Therapy in Patients With Multiple Sclerosis | Neurology - 1 month(s) ago
Background and ObjectivesOutcome reporting bias occurs when publication of trial results is dependent on clinical significance, thereby threatening the validity of trial results. Research on immunomodulatory drugs in multiple sclerosis has thrived in …
Source: www.neurology.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 112Practical Considerations for Managing Pregnancy in Patients With Multiple Sclerosis: Dispelling the Myths: Neurology Clinical Practice: Vol 14, No 2 - 2 month(s) ago
Purpose of ReviewLack of consistent data and guidance have led to variations between clinicians in the management of pregnancy in women with multiple sclerosis (MS). Pregnant and/or lactating women are often excluded from clinical trials conducted in MS, …
Source: www.neurology.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 36Effect of Evobrutinib on Slowly Expanding Lesion Volume in Relapsing Multiple Sclerosis: A Post Hoc Analysis of a Phase 2 Trial: Neurology: Vol 102, No 5 - 2 month(s) ago
Background and ObjectivesChronic active lesions (CALs) are demyelinated multiple sclerosis (MS) lesions with ongoing microglia/macrophage activity, resulting in irreversible neuronal damage and axonal loss. Evobrutinib is a highly selective, covalent, CNS-…
Source: www.neurology.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 81MOG Antibodies Restricted to CSF in Children With Inflammatory CNS Disorders | Neurology - 2 month(s) ago
ObjectivesTo assess the clinical significance of myelin oligodendrocyte glycoprotein antibodies (MOG-abs) restricted to CSF in children with inflammatory CNS disorders.MethodsPatients included 760 children (younger than 18 years) from 3 multicenter …
Source: www.neurology.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 20Disparities by Race in Pregnancy Care and Clinical Outcomes in Women With Multiple Sclerosis: A Diverse Multicenter Cohort: Neurology: Vol 102, No 4 - 2 month(s) ago
Background and ObjectivesRacial disparities exist in both neurologic and obstetric populations, underscoring the importance of evaluating pregnancy outcomes in diverse women with multiple sclerosis (MS). The objective of this multicenter retrospective …
Source: www.neurology.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 28Outcome Reporting Bias in Clinical Trials Researching Disease-Modifying Therapy in Patients With Multiple Sclerosis | Neurology - 2 month(s) ago
Background and ObjectivesOutcome reporting bias occurs when publication of trial results is dependent on clinical significance, thereby threatening the validity of trial results. Research on immunomodulatory drugs in multiple sclerosis has thrived in …
Source: www.neurology.orgCategories: General Medicine News, NeurologyTweet
Practical Considerations for Managing Pregnancy in Patients With Multiple Sclerosis: Dispelling the Myths https://t.co/U3El5ktTmj #NeuroTwitter #MS https://t.co/9HBLXi2pyo