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Mashup Score: 121Teaching NeuroImage: A 2-Year-Old Girl With Molybdenum Cofactor Deficiency | Neurology - 11 day(s) ago
A 2-year-old girl with global developmental delay presented with generalized tonic-clonic seizures and dystonic posturing but without history of hypoxia, asphyxia, or jaundice. Brain MRI revealed bilateral symmetric basal ganglia and parieto-occipital cortical lesions (Figure, A–D). MRS showed significant parieto-occipital lipid-lactate peaks (Figure, E). EEG showed background slowing and epileptic discharges in bilateral occipital regions. Blood uric acid and homocysteine conce ntrations were reduced
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Mashup Score: 83Pearls & Oy-sters: Thyroid-Associated Ophthalmopathy and Transient Neuromuscular Junction Disorder Due to Graves Disease | Neurology - 14 day(s) ago
The concomitant presentation of thyroid-associated ophthalmopathy (TAO) and ocular myasthenia gravis is well documented. In the course of Graves disease (GD), symptomatic transient neuromuscular junction disorder may occur due to the effect of thyroid …
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Mashup Score: 16Bridging the Gap: Local Field Potentials Offer a Peek Into the Brain of a Person With Parkinson Disease | Neurology - 18 day(s) ago
Clinically available deep brain recordings in patients with Parkinson disease (PD) offer insights into disease mechanisms and create a pathway for personalized treatment strategies. This case illustrates the transformative potential of recordings of …
Source: www.neurology.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 175Teaching NeuroImage: Mitochondrial Membrane Protein-Associated Neurodegeneration: An MRI Pattern Recognition: Neurology: Vol 102, No 9 - 18 day(s) ago
A 12-year-old girl born to third-degree consanguineous parents presented with 2 years of progressive dystonia starting in both lower limbs followed by upper limbs, along with dysarthria, numbness, and bladder incontinence. Examination revealed dystonia, spasticity, and brisk reflexes. MRI brain showed T2-weighted and susceptibility-weighted imaging hypointensity in bilateral globus pallidi (Figure, A and B) with sparing of the medial medullary lamina and hypointensity in substantia nigra (Figure, C and
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Mashup Score: 76Clinical Reasoning: A 24-Year-Old Man With Gait Impairment, Hearing Loss, and Recurrent Fever | Neurology - 23 day(s) ago
We present a case study of a 24-year-old man who reported mild balance and walking difficulties for 2 years. He had a history of recurrent fever, skin lesions, headache, and elbow pain, but most of these events resolved spontaneously. There was no …
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Mashup Score: 43Teaching NeuroImage: Extramedullary Hematopoiesis Leading to Spinal Cord Compression | Neurology - 1 month(s) ago
A 70-year-old man with myelodysplastic syndrome currently undergoing erythropoiesis stimulation therapy with luspatercept presented with worsening bilateral leg weakness and urinary retention. He had bilateral patellar hyperreflexia, but absent Achilles reflexes and plantar responses bilaterally. T-spine MRI was obtained, which showed extensive T2 hyperintense and enhancing soft-tissue masses in the epidural space compressing the spinal cord, suggestive of possible extramedullary hematopoiesis (EMH) (see
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Mashup Score: 73Pearls & Oy-sters: Thyroid-Associated Ophthalmopathy and Transient Neuromuscular Junction Disorder Due to Graves Disease | Neurology - 1 month(s) ago
The concomitant presentation of thyroid-associated ophthalmopathy (TAO) and ocular myasthenia gravis is well documented. In the course of Graves disease (GD), symptomatic transient neuromuscular junction disorder may occur due to the effect of thyroid …
Source: www.neurology.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 109Teaching NeuroImage: A 2-Year-Old Girl With Molybdenum Cofactor Deficiency | Neurology - 1 month(s) ago
A 2-year-old girl with global developmental delay presented with generalized tonic-clonic seizures and dystonic posturing but without history of hypoxia, asphyxia, or jaundice. Brain MRI revealed bilateral symmetric basal ganglia and parieto-occipital cortical lesions (Figure, A–D). MRS showed significant parieto-occipital lipid-lactate peaks (Figure, E). EEG showed background slowing and epileptic discharges in bilateral occipital regions. Blood uric acid and homocysteine conce ntrations were reduced
Source: www.neurology.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 43Teaching NeuroImage: Dialysis-Related Spondyloarthropathy: An Unexpected Cause of Back Pain: Neurology: Vol 102, No 8 - 1 month(s) ago
A 68-year-old woman with a 15-year history of end-stage renal disease requiring hemodialysis because of polycystic kidney disease presented with 8 years of worsening bilateral lumbar pain. The shock-like pain radiated down her posterior and lateral legs to her feet and was accompanied by numbness. Physical examination revealed bilateral and symmetrical weakness (Medical Research Council grade 4/5) in hip flexion, knee extension, and knee flexion, along with mild symmetric sensory loss in the L4, L5, and
Source: www.neurology.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 11Bridging the Gap: Local Field Potentials Offer a Peek Into the Brain of a Person With Parkinson Disease | Neurology - 1 month(s) ago
Clinically available deep brain recordings in patients with Parkinson disease (PD) offer insights into disease mechanisms and create a pathway for personalized treatment strategies. This case illustrates the transformative potential of recordings of …
Source: www.neurology.orgCategories: General Medicine News, NeurologyTweet
A 2-year-old girl with global developmental delay presented with generalized tonic-clonic seizures and dystonic posturing but without history of hypoxia, asphyxia, or jaundice. Learn more in this Teaching NeuroImage article: https://t.co/YP5kUriRKz #NeurologyRF #NeuroTwitter https://t.co/5iJl9S3bap