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    von Hippel-Lindau (VHL) disease is a rare autosomal-dominant hereditary disease characterized by mutation of the VHL gene. This gene encodes for the VHL protein, which regulates the activity of HIF-α, a transcription factor involved in the cellular response to hypoxia. Mutations in VHL lead to the accumulation of HIF-α and, consequently, the engagement of hypoxia-sensitive genes with tumorigenic…

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    • Case report by @pelle_eleonora, @altoubaht, Brian Morse, MD, and Jonathan Strosberg, MD, of @MoffittNews describes near-complete response to belzutifan in patient with VHL-associated metastatic pancreatic #neuroendocrinetumor: https://t.co/th7d99i9s7 #NeuroendocrineCancer #PNET https://t.co/hezQPVqnz9

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    By the time Alabama resident Susan Waldrop was diagnosed with a rare neuroendocrine tumor called pheochromocytoma, she’d been suffering from symptoms for almost five years. At MD Anderson, surgery and a clinical trial put her in remission — and the clinical trial she participated in led to the first FDA approval of a drug to treat this rare disease.

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    • Susan Waldrop joined a clinical trial at MD Anderson that put her sporadic metastatic pheochromocytoma in remission. Read how our Dr. Camilo Jimenez gave her hope: https://t.co/nfTWFR7igc #NeuroendocrineTumor #EndCancer

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    The Cancer News Daily - 2 year(s) ago

    The latest in cancer medicine and translational research by Wafik El-Deiry MDPhD

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    • The latest The Cancer News Daily! https://t.co/4PnERpxswB Thanks to @HopkinsMedicine #oncology #neuroendocrinetumor

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    Share with friendsChyna Woods was like many people during the pandemic — busy working from home and caring for her grandmother — until pain between her shoulder blades made sitting in her desk chair unbearable. “I had extremely excruciating back pain. I couldn’t lay or sit down for long periods of time,” says Woods. “I couldn’t even […]

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    • RT @CarcinoidNETs: Young Woman's Back Pain Turns out to Be Rare #NeuroendocrineTumor- a #paraganglioma https://t.co/Tl8U7mcWQg #pheo #para…