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Mashup Score: 16An antibiotic preorganized for ribosomal binding overcomes antimicrobial resistance - 3 month(s) ago
A synthetic molecule preorganized for bacterial ribosome binding is highly effective against multi-drug-resistant bacteria
Source: www.science.orgCategories: General Medicine News, Future of MedicineTweet
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Mashup Score: 19
Nature Medicine – A soft wearable robotic device significantly reduces freezing of gait in a single individual with Parkinson’s disease.
Source: www.nature.comCategories: General Medicine News, Future of MedicineTweet
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Mashup Score: 200
Nature – A tethered macrocyclic peptide antibiotic class described here—which shows potent antibacterial activity against carbapenem-resistant Acinetobacter baumannii—blocks the…
Source: www.nature.comCategories: General Medicine News, Future of MedicineTweet
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Mashup Score: 129Uncovering the functional diversity of rare CRISPR-Cas systems with deep terascale clustering - 4 month(s) ago
A clustering algorithm, FLSHclust, was developed and applied to discover 188 previously unreported CRISPR-linked gene modules.
Source: www.science.orgCategories: General Medicine News, Future of MedicineTweet
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Mashup Score: 77Pan-cancer analysis of post-translational modifications reveals shared patterns of protein regulation - 5 month(s) ago
An analytical resource of post-translational modifications from over 1,000 patients across 11 cancer types reveals pan-cancer changes involved in hallmark cancer processes and reveals potential new therapeutic avenues.
Source: www.cell.comCategories: General Medicine News, Future of MedicineTweet
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Mashup Score: 93N1-methylpseudouridylation of mRNA causes +1 ribosomal frameshifting - 5 month(s) ago
Nature – A study demonstrates that nucleotide modifications in mRNA-based therapeutics can lead to +1 ribosomal frameshifting during translation, yielding products that can trigger immune responses.
Source: www.nature.comCategories: General Medicine News, Future of MedicineTweet
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Mashup Score: 34Targeted design of synthetic enhancers for selected tissues in the Drosophila embryo - 5 month(s) ago
Nature – Targeted design of synthetic enhancers for selected tissues in the Drosophila embryo
Source: www.nature.comCategories: General Medicine News, Future of MedicineTweet
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Mashup Score: 20Trans-vaccenic acid reprograms CD8+ T cells and anti-tumour immunity - 5 month(s) ago
Nature – A screen of nutrient-derived compounds identified trans-vaccenic acid as a promoter of effector T cell function, and functional assays demonstrate that this occurs via inactivation of…
Source: www.nature.comCategories: General Medicine News, Future of MedicineTweet
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Mashup Score: 79
In temporally multiplexed imaging (TMI), many dynamic signals can be imaged in the same living cell, using a standard microscope, by associating different cellular signals with genetically encoded fluorophores with distinct clocklike properties.
Source: www.cell.comCategories: General Medicine News, Future of MedicineTweet
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Mashup Score: 116Uncovering the functional diversity of rare CRISPR-Cas systems with deep terascale clustering - 5 month(s) ago
A clustering algorithm, FLSHclust, was developed and applied to discover 188 previously unreported CRISPR-linked gene modules.
Source: www.science.orgCategories: General Medicine News, Future of MedicineTweet
An antibiotic designed using component-based synthesis is shown to be highly effective against antimicrobial resistance mechanisms and multi-drug resistant strains of gram-negative and -positive bacteria. #NBThighlight https://t.co/D7GIXmCr4l