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Mashup Score: 6Kalyan Banda, MD - 8 month(s) ago
Patient provider profile for Dr. Kalyan Banda, medical oncologist at Fred Hutchinson Cancer Center.
Source: www.fredhutch.orgCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 0Aspects of Molecular Medicine - Journal - Elsevier - 1 year(s) ago
Aspects of Molecular Medicine is a gold open access journal with the goal of rapidly publishing new research articles and short reviews on the molecular and c…
Source: www.journals.elsevier.comCategories: Genetics, Latest HeadlinesTweet
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Mashup Score: 0Aspects of Molecular Medicine - Journal - Elsevier - 2 year(s) ago
Aspects of Molecular Medicine is a gold open access journal with the goal of rapidly publishing new research articles and short reviews on the molecular and c…
Source: www.journals.elsevier.comCategories: Genetics, Latest HeadlinesTweet
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Mashup Score: 0
POH1/Rpn11/PSMD14 is a highly conserved protein in eukaryotes from unicellular organisms to human and has a crucial role in cellular homoeostasis. It is a subunit of the regulatory particle of the proteasome, where it acts as an intrinsic deubiquitinase removing polyubiquitin chains from substrate proteins. This function is not only coupled to the translocation of substrates into the core of the…
Source: NatureCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 1RANKL regulates testicular cancer growth and Denosumab treatment has suppressive effects on GCNIS and advanced seminoma - 2 year(s) ago
Testicular germ cell tumours (TGCTs) have a high sensitivity to chemotherapy and a high cure rate, although with serious adverse effects. In the search for tumour suppressive drugs, the RANKL inhibitor Denosumab, used to treat osteoporosis, came up as a candidate since RANKL signalling was recently identified in the testis. Expression of RANKL, RANK and OPG, and the effects of RANKL inhibition…
Source: www.nature.comCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 0
The diagnosis and surveillance of urothelial bladder cancer (UBC) require cystoscopy. There is a need for biomarkers to reduce the frequency of cystoscopy in surveillance; urinary volatile organic compound (VOC) analysis could fulfil this role. This cross-sectional study compared the VOC profiles of patients with and without UBC, to investigate metabolomic signatures as biomarkers. Urine samples…
Source: NatureCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 1
Testicular germ cell tumours (TGCTs) have a high metastasis rate. However, the mechanisms related to their invasion, progression and metastasis are unclear. Therefore, we investigated gene expression changes that might be linked to metastasis in seminomatous testicular germ cell tumour (STGCT) patients. Defined areas [invasive tumour front (TF) and tumour centre (TC)] of non-metastatic (with…
Source: NatureCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 2NTRK1 Fusions identified by non-invasive plasma next-generation sequencing (NGS) across 9 cancer types - 2 year(s) ago
Activating fusions of the NTRK1, NTRK2 and NTRK3 genes are drivers of carcinogenesis and proliferation across a broad range of tumour types in both adult and paediatric patients. Recently, the FDA granted tumour-agnostic approvals of TRK inhibitors, larotrectinib and entrectinib, based on significant and durable responses in multiple primary tumour types. Unfortunately, testing rates in clinical…
Source: www.nature.comCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 60Antibody-like proteins that capture and neutralize SARS-CoV-2 - International Natural Product Sciences Taskforce - 3 year(s) ago
Abstract To combat severe acute respiratory syndrome–related coronavirus 2 (SARS-CoV-2) and any unknown emerging pathogens in the future, the development of a rapid and effective method to generate high-affinity antibodies or antibody-like proteins is of critical importance. We here report high-speed in vitro selection of multiple high-affinity antibody-like proteins against various targets…
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Mashup Score: 0
Molecular and Precision Medicine (MAP) Series A five-part virtual series presented Wednesdays from 8:00-9:00 AM ET, hosted on an event platform that includes a dedicated “exhibit hall.” Each session…
Source: sto-online.orgCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
Get to know Kalyan Banda, MD! Dr. Banda is a Fred Hutch medical oncologist who specializes in gynecological and breast cancers. In the lab, Dr. Banda focuses on using #molecularmedicine to accurately predict a patient’s response or resistance to treatment. https://t.co/cE1doRusXq https://t.co/cj89eYtRBV