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Mashup Score: 0Additional PIONEER Study Results Back FDA Priority Review for Avapritinib in Indolent Systemic Mastocytosis - 1 year(s) ago
The developer of avapritinib has announced full registrationL results from the phase 2 PIONEER study of avapritinib for the treatment of indolent systemic mastocytosis.
Source: Targeted OncologyCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 0Prognostic Impact of Organomegaly in Mastocytosis: An Analysis of the European Competence Network on Mastocytosis - 1 year(s) ago
Organomegaly, including splenomegaly, hepatomegaly, and/or lymphadenopathy, are important diagnostic and prognostic features in patients with cutaneous mastocytosis (CM) or systemic mastocytosis (SM).
Categories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 0Hematopoietic KIT D816Y mutation presenting as in utero aggressive systemic mastocytosis with response to midostaurin - 1 year(s) ago
Dayne Voelker, MD Dayne VoelkerAffiliationsDepartment of Medicine, Division of Allergy and Immunology, Washington University School of Medicine, St. Louis, MOJeffrey J. Bednarski, MD PhD Jeffrey J. BednarskiAffiliationsDepartment of Pediatrics, Division of Hematology-Oncology, Washington University School of Medicine, St. Louis, MOSearch for articles by this authorElizabeth Nieman, MD Elizabeth…
Categories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 0Avapritinib for advanced systemic mastocytosis - 2 year(s) ago
Abstract. Avapritinib, a highly selective inhibitor of KIT D816V, was approved by the Food and Drug Administration in 2021 for treatment of advanced systemic ma
Source: American Society of HematologyCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 0Pooled Analysis Shows Good Results With Avapritinib in Previously Treated Advanced SM | ASH Clinical News | American Society of Hematology - 2 year(s) ago
Skip Nav Destination August 30, 2022 A pooled analysis of two clinical trials on advanced systemic mastocytosis (SM) showed that previously treated patients responded well to the kinase-​inhibitor avapritinib, according to findings published in…
Source: ashpublications.orgCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 0Systemic Mastocytosis Treatment Options - 2 year(s) ago
What are the treatment options for systemic mastocytosis (SM)? Two SM experts explain.
Source: Patient PowerCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 0“I Was Pregnant, So I Researched My Mastocytosis.” - 2 year(s) ago
A systemic mastocytosis (SM) patient describes her diagnosis journey, from her early twenties through undergoing the protocol for a pregnant SM patient when she had her daughter.
Source: Patient PowerCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 0Findings That Lead to a Systemic Mastocytosis Diagnosis - 2 year(s) ago
How is systemic mastocytosis diagnosed? An expert explains.
Source: Patient PowerCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 0What Are the Types of Systemic Mastocytosis? - 2 year(s) ago
Systemic mastocytosis (MS) is a rare chronic blood disease that has both non-advanced and advanced subtypes. Learn more.
Source: Patient PowerCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 0
Systemic mastocytosis (SM) is a heterogeneous group of disorders characterized by clonal mast cell expansion within the hematopoietic compartment and other tissues. Patients present with manifestations ranging from cutaneous to systemic symptoms relating to mast cell mediator release and/or tissue infiltration. SM is currently classified into one of several variants: indolent SM (ISM), smoldering…
Categories: Allergy-Immunology, Latest HeadlinesTweet
#Avapritinib showed statistically significant & clinically meaningful improvements in TSS that deepened over time for patients with indolent systemic #mastocytosis, meeting the primary end point of the phase 2 PIONEER study. @BrighamWomens https://t.co/ETzVtbzQPP