Low-dose computed tomography (LDCT) screening for lung cancer significantly reduces mortality from lung cancer, as demonstrated in randomized controlled trials and meta-analyses. This review is based on the ninth CT screening symposium of the International Association for the Study of Lung Cancer (IASLC) which focuses on the major themes pertinent to the successful global implementation of LDCT screening and developed a strategy to further the implementation of lung cancer screening globally.These recommendations provide a 5-year road map to advance the implementation of LDCT screening globally including: (i) establishing universal screening program quality indicators; (ii) establishing evidence-based criteria to identify individuals who have never smoked but are at high risk of developing lung cancer; (iii) develop recommendations for incidentally detected lung nodule tracking and management protocols to complement programmatic lung cancer screening; (iv) Integrate artificial intellig