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Mashup Score: 3
Introduction Immune checkpoint inhibitors (ICIs) have changed the treatment landscape for multiple cancer types. Sex plays an important role in both the development of cancer as well as the functioning of the immune system. Though a difference in response to immune therapy is emerging between men and women it is unclear how this difference affects cancer outcomes and what the potential underlying…
Source: BMJ OpenCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 1Systematic lncRNA mapping to genome-wide co-essential modules uncovers cancer dependency on uncharacterized lncRNAs - 2 year(s) ago
The discovery of uncharacterized lncRNAs that regulate cell proliferation/growth across cancer types, including two p53 regulated tumor suppressive lncRNAs, were identified through systematic analyses of multi-omics data and provides a computational framework resource to cancer researchers.
Source: eLifeCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
SKCC's Dr. Chris Eischen and team discuss the function of non-coding RNAs (lncRNAs) in cancer formation and progression: https://t.co/XsAcCVOaSB @eLife #JeffersonResearch
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Mashup Score: 2
Intrahepatic Delivery of SD-101 by Pressure-Enabled Regional Immuno-oncology (PERIO), With Checkpoint Blockade in Adults With Metastatic Uveal Melanoma – Full Text View.
Source: www.clinicaltrials.govCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
#TrialTuesday: SKCC's Dr. Marlana Orloff and team are investigating the effectiveness of SD-101, a TLR 9 agonist, in patients with #UvealMelanoma that has spread to the liver: https://t.co/zaBOFKUZN4 @TriSalusLifeSci #ClinicalTrial #OcularMelanoma #JeffersonResearch https://t.co/xjabvpUE1R
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Mashup Score: 0Extracellular matrix guidance of autophagy: a mechanism regulating cancer growth | Open Biology - 2 year(s) ago
The extracellular matrix (ECM) exists as a dynamic network of biophysical and biochemical factors that maintain tissue homeostasis. Given its sensitivity to changes in the intra- and extracellular space, the plasticity of the ECM can be pathological in …
Source: Open BiologyCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
New review in #OpenBiology: ➡️ Jefferson's Carolyn Chen & Dr. @iozzo_v discuss how further investigation is necessary to better understand the disease-driving impact of the #ExtracellularMatrix in carcinogenesis: https://t.co/4phJqh4kMh @royalsociety #JeffersonResearch https://t.co/uLgiVARjMg
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Mashup Score: 0
Metrics used to compare lung cancer surgical performance between providers have varying levels of reliability. Reliability should be considered when profiling providers, which will become particularly important as lung cancer treatment under screening programs continues to expand.
Source: PubMedCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
Learn more about this exciting new #JeffersonResearch in #LungCancer surgery! https://t.co/iHjhuPSfb3 #ResearchWednesday https://t.co/WaOk53JPMV
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Mashup Score: 3
Multiparametric MRI in Evaluating Cancer Stage and Helping Treatment Planning in Patients With Prostate Cancer – Full Text View.
Source: www.clinicaltrials.govCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
#TrialTuesday: A #ClinicalTrial led by SKCC & @JEFFUrology's Dr. Edouard Trabulsi that will help determine if multiparametric #MRI is useful for patients with #ProstateCancer: https://t.co/J4r4DZyqNZ @eaonc #ProstateCancerAwarenessMonth #PCAM #JeffersonResearch https://t.co/vTyCAj818G
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Mashup Score: 3Tevogen Bio to Initiate Clinical Trial of its Investigational T Cell Therapy for COVID-19 at Thomas Jefferson University - 3 year(s) ago
Tevogen Bio to begin clinical trial of TVGN-489, a novel T cell therapy for high risk COVID-19 patients, at Thomas Jefferson University, Philadelphia.
Source: www.businesswire.comCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
SKCC's Dr. Dolores Grosso is the PI of a new #ClinicalTrial to evaluate whether @TevogenBio's investigational #Covid19 T-cell therapy is safe and effective in eliminating the virus in high-risk patients. Learn more: https://t.co/VN2AG90772 @ResearchAtJeff #JeffersonResearch
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Mashup Score: 0
Few African American individuals with cancer completed advance directives despite a high level of advance care planning readiness in this population, according to results presented at the virtual Oncology Nursing Society Congress.“We were pleased to see higher rates of advance care planning conversations and advanced directive completion in our sample compared with national averages. We
Source: www.healio.comCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
Learn more about this important #JeffersonResearch led by Dr. @JeannetteKates and team: https://t.co/GXWYOODCLq @ResearchAtJeff #palliativecare #advancedirectives #cancerdisparities #oncologynursing via @HemOncToday https://t.co/walcBHqK1R
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Mashup Score: 6Bispecific Fusion Protein Tebentafusp Significantly Improves Overall Survival in Patients With Metastatic Uveal Melanoma | AACR | News Releases - 3 year(s) ago
Compared with available standard therapies, including immune checkpoint inhibitors, treatment with the bispecific fusion protein tebentafusp nearly halved the risk of death among patients with metastatic uveal melanoma, according to results of a phase III clinical trial presented during Week 1 of the virtual AACR Annual Meeting 2021, held April 10-15.
Categories: Hem/Onc News and Journals, Latest HeadlinesTweet-
Study results presented at #AACR21 showed that tebentafusp improves overall survival among patients with advanced #uvealmelanoma. SKCC's Dr. Marlana Orloff, who was one of the study authors, said this could be "practice changing." https://t.co/pjYWUkAs6M #JeffersonResearch https://t.co/jf4ThdqzJZ
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Mashup Score: 2Facebook - 3 year(s) ago
Sidney Kimmel Cancer Center – Jefferson Health 4 hrs SKCC Researcher Spotlight: Josep Domingo-Domenech, MD, PhD, co-leader of the SKCC Molecular Oncology Regulation & Approaches ProgramDr. Domingo-Domenech and his laboratory’s main focus is to assess the mechanisms contributing to the way lethal cancer develops, mainly in genitourinary tumors (specifically prostate and bladder cancers). The team…
Source: www.facebook.comCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
SKCC Researcher Spotlight: Dr. @DomingoDomenech, co-leader of the SKCC Molecular Oncology Regulation & Approaches Program: https://t.co/xWJZ1H3sGX #prostatecancer #bladdercancer #JeffersonResearch #GUcancer https://t.co/uacFK1y65u
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New #JeffersonResearch led by SKCC's Dr. Amy Shaver & Dr. Grace Lu-Yao explores the influence that sex has on the outcomes experienced by cancer patients on immune checkpoint inhibitor therapy: https://t.co/hGZOFHnGbh @BMJ_Open #ResearchWednesday https://t.co/51yzX2ezlZ