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Mashup Score: 13Skeletal Muscle Involvement in Patients With Truncations of Titin and Familial Dilated Cardiomyopathy: - 30 day(s) ago
AbstractBackgroundGenetic variants in titin (TTN) are associated with dilated cardiomyopathy (DCM) and skeletal myopathy. However, the skeletal muscle phenotype in individuals carrying heterozygous…
Source: www.jacc.orgCategories: General Medicine News, Partners & KOLsTweet
Study reveals that patients with truncating titin variants exhibit higher fat replacement in skeletal muscles, myopathic features in biopsies, with potential disruptions in autophagy and mitochondrial dynamics. Details: https://t.co/IEqRlUaxi5 #JACCHF #TTNtv #Cardiomyopathy #DCM https://t.co/r357p0cLFD