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Mashup Score: 27Failure to Launch: Insights From Randomized Trials on Implementation Strategies for Guideline-Directed Therapies for Heart Failure - 6 day(s) ago
AbstractThere is a pressing need to translate evidence for heart failure (HF) therapies into contemporary practice. Medications that improve HF morbidity and mortality remain underused because of c…
Source: www.jacc.orgCategories: General Medicine NewsTweet
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Mashup Score: 8UNa+ Levels Associated With Mortality, Hospitalizations in Patients With HF - American College of Cardiology - 20 day(s) ago
Longitudinal levels of pre-diuretic spot urinary sodium (UNa+) showed a decreasing trajectory over time in ambulatory outpatients with stable, chronic heart failure (HF), and lower levels of UNa+ were associated with increased risks in all-cause mortality and long-term, HF-related hospitalizations, according to a brief report published in JACC: Heart Failure. In the ob servational, single-center prospective study conducted in Spain, Miguel Lorenzo, MD, et al., assessed 5,126 UNa+ determinations (collected
Source: www.acc.orgCategories: General Medicine NewsTweet-
Longitudinal levels of pre-diuretic spot UNa+ showed a ↘️ trajectory over time in ambulatory outpatients w/ stable, chronic HF, & lower levels of UNa+ were associated w/ ↗️ risks in all-cause mortality & long-term, HF-related hospitalizations. 🔗 https://t.co/uFX7pQALn4 #JACCHF https://t.co/eWMl1vWQQC
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Mashup Score: 14Is Aficamten Plus Disopyramide More Effective Than Aficamten Alone in oHCM? - American College of Cardiology - 1 month(s) ago
The addition of aficamten to disopyramide was effective and well-tolerated in patients with symptomatic obstructive hypertrophic cardiomyopathy (oHCM) with persistent left ventricular overflow tract (LVOT) obstruction, and the withdrawal of disopyramide did not reduce the effectiveness of aficamten, according to research published May 7 in JACC: Heart Failure. Ahmad Masri, MD, FACC, et al., drew from three trials of patients with oHCM: the open-label REDWOOD-HCM Cohort 3, the placebo-controlled SEQUOIA-HCM
Source: www.acc.orgCategories: General Medicine NewsTweet
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Mashup Score: 4Donor Hearts Fare Better With Novel Method After Circulatory Death - 1 month(s) ago
The controversial taNRP protocol shortens ischemic time for donations after circulatory death and improves outcomes.
Source: www.tctmd.comCategories: General Medicine NewsTweet
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Mashup Score: 11DCD Heart Transplantation With taNRP vs. DPP: Outcomes at 1 Year - American College of Cardiology - 1 month(s) ago
Donation after circulatory determination of death (DCD) heart transplant recipients with hearts retrieved via thoraco-abdominal normothermic regional perfusion (taNRP) were less likely to have severe primary graft dysfunction (PGD) and exhibited fewer episodes of biopsy-proven acute-cellular rejection (ACR) at one year compared to those with hearts retrieved through direct procurement and perfusion (DPP), according to an international, multicenter study presented at ISHLT 2025 and simultaneously published
Source: www.acc.orgCategories: General Medicine NewsTweet
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Mashup Score: 129Evaluation of the Hemocompatibility of the Direct Oral Anticoagulant Apixaban in Left Ventricular Assist Devices: The DOAC LVAD Study - 4 month(s) ago
AbstractBackgroundPatients receiving left ventricular assist device (LVAD) support require long-term anticoagulation to reduce the risk of thromboembolic complications. Apixaban is a direct oral an…
Source: www.jacc.orgCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 25Growth Differentiation Factor–15 Is Associated With Congestion-Related Anorexia and Weight Loss in Advanced Heart Failure: - 4 month(s) ago
AbstractBackgroundGrowth differentiation factor (GDF)-15 is a pleiotropic cytokine that is associated with appetite-suppressing effects and weight loss in patients with malignancy.ObjectivesThis st…
Source: www.jacc.orgCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 55Diuretic Potentiation Strategies in Acute Heart Failure: - 5 month(s) ago
AbstractSeveral trials have evaluated diuretic-based strategies to improve symptoms and outcomes in patients with acute heart failure (AHF). The authors sought to summarize the effect of different …
Source: www.jacc.orgCategories: General Medicine News, Partners & KOLsTweet-
#JACCHF: https://t.co/xA9Jzr8qtE Intensification of loop diuretic agents relieves physical signs of decongestion, but the importance of different strategies (such as adding vasopressin antagonists) for short-term decongestion strategy for health status & long-term outcomes has… https://t.co/EZymz99qdU https://t.co/pJwqs2RaQQ
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Mashup Score: 48Automated Identification of Heart Failure With Reduced Ejection Fraction Using Deep Learning-Based Natural Language Processing: - 5 month(s) ago
AbstractBackgroundThe lack of automated tools for measuring care quality limits the implementation of a national program to assess guideline-directed care in heart failure with reduced ejection fra…
Source: www.jacc.orgCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 15Mineralocorticoid Antagonism in Heart Failure: Established and Emerging Therapeutic Role - 6 month(s) ago
AbstractThe pathophysiology of heart failure (HF) is related to the overactivation of the mineralocorticoid receptor, leading to fluid retention and adverse myocardial remodeling. Although mineralo…
Source: www.jacc.orgCategories: General Medicine News, CardiologistsTweet
💫 New in #JACCHF @JACCJournals 📰 Failure to Launch: Insights From Randomized Trials on Implementation Strategies for Guideline-Directed Therapies for Heart Failure Review discuss barriers to GDMT, implementation strategies and potential solutions 🔗https://t.co/LfZbFxBOTk https://t.co/yCqx1bIdMH