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Mashup Score: 9Stability of Ready-to-Use Solutions of Acetylcholine for Intracoronary Provocative Testing: - 5 day(s) ago
Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology and University Tübingen, Stuttgart, Germany Robert Bosch Hospital, Stuttgart, Germany Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology and University Tübingen, Stuttgart, Germany Drs Mürdter and Ong contributed equally to this work. Robert Bosch Hospital, Stuttgart, Germany Drs Mürdter and Ong contributed equally to this work. Coronary vasomotor disorders play an important role in the pathogenesis of angina pectoris and coronary
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Mashup Score: 10Targeting the Gut-Heart Axis Improves Cardiac Remodeling in a Clinical Scale Model of Cardiometabolic Syndrome: - 19 day(s) ago
Highlights •In a porcine model of metabolic syndrome, HFpEF, and atrial myopathy, the full extent of the inflammatory GHA is demonstrated.•The GHA extends from gut dysbiosis, barrier function loss,…
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Dr. Florence M. Herisson et al. show the gut microbiome’s key role in heart disease and how a probiotic cross-fed with a fiber can reduce it. This could lead to breakthrough therapies for heart disease https://t.co/7l3N4MoOfq #JACCBTS https://t.co/5ebBF28H44
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Mashup Score: 1Knowing Your ABCs: Macrophage ABCA1-Mediated Cholesterol Efflux as a Therapeutic Target in Atherosclerotic Cardiovascular Disease - 1 month(s) ago
Corresponding Authors
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In this #JACCBTS editorial, Drs. George A. Karpouzas and Nicoletta Ronda discuss a recent report of a role for ABCA1 superenhancer RNA in regulating cholesterol efflux. https://t.co/a35YAgRjDh
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Mashup Score: 8Introducing the 2024 Transcatheter Cardiovascular Therapeutics (TCT) Shark Tank Presentations: - 2 month(s) ago
∗Address for correspondence: Dr Douglas L. Mann, Division of Cardiology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri 63110, USA. E-mail: E-mail Address: [email protected] The editors of JACC: Basic to Translational Science are pleased to feature 3 outstanding Shark Tank presentations from the 2024 Transcatheter Cardiovascular Therapeutics (TCT) meeting, held in Washington, DC, from October 27 to 30, 2024. The TCT is one of the most significant global meetings
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In this #JACCBTS article, EiC Dr. @DLMann_MD introduces the three Transcatheter Cardiovascular Therapeutics (TCT) Shark Tank presentations for this year: https://t.co/BEGqxJtauW @TCTConference https://t.co/ehTtLOiVqc
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Mashup Score: 44Pericardial Fluid of Patients With Coronary Artery Disease Can Drive Fibrosis Via TGF-Beta Pathway: - 2 month(s) ago
Highlights •Human PF contains inflammatory mediators, including cytokines, chemokines, and growth factors.•Reflecting a dynamic space, disease states can influence the inflammatory mediator profile…
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💡 https://t.co/wouqyTopGJ #JACCBTS study provides insight into the inflammatory profile of the human PF, offers clues on the sources of these local markers, shows that different diseases can affect the composition of the mediator profile, & suggests that human PF can drive… https://t.co/e0ZzV27uIq https://t.co/wi08XdExS3
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Mashup Score: 15Charting New Real Estate: Leveraging the Therapeutic Potential of the Pericardial Space - 3 month(s) ago
Corresponding Author
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In this editorial, authors discuss approaches to gain access to the pericardial space in animal models, including a recent #JACCBTS methods article on permanent pericardial access in mice. https://t.co/pqA54zAp5i https://t.co/Fev5vhnlsh
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Mashup Score: 13Call For Applications: JACC: Basic to Translational Science Editor in Chief - American College of Cardiology - 3 month(s) ago
The ACC is seeking its next editor in chief for JACC: Basic to Translational Science (JACC: BTS), an exciting leadership opportunity for a visionary and dynamic thinker eager to shape the future of cardiovascular basic to translational science. JACC: BTS has established itself as a leading journal in translational science and is poised for a bold evolution. With the journal’s platform ideally positioned to propel the field forward, the College is seeking an individual with a compelling vision for addressin
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ACC is seeking its next editor in chief for #JACCBTS, an exciting leadership opportunity for a visionary & dynamic thinker eager to shape the future of cardiovascular basic to translational science. Applications due Dec. 20, 2024! Learn more: https://t.co/d53HQJxpNW… https://t.co/K7Rgsm6uAV https://t.co/OxCrY5v1v1
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Mashup Score: 7JACC: Basic to Translational Science - 5 month(s) ago
View the JACC: Basic to Translational Science landing page, led by Dr. Douglas Mann.
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Check out the latest #JACCBTS tweetorial from @uclaCVfellows ⭐️ @MichaelR21 New issue @JACCJournals now up: https://t.co/FJ0j7tmAn0 @DLMann_MD @VascRes @Jean_Wassenaar https://t.co/4GgAdZgPis
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Mashup Score: 8A New Ex Vivo Model to Study Cardiac Fibrosis in Whole Mouse Hearts: - 5 month(s) ago
Highlights •No effective pharmacological treatment exists for cardiac fibrosis caused by absence of relevant preclinical translational models.•This study demonstrates the development of an ex vivo …
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In this #JACCBTS article, authors describe an ex vivo rodent cardiac fibrosis model that allows the study of the cellular and molecular mechanisms underlying cardiac fibrosis and can serve as a pre-clinical test system for new targets for fibrosis. https://t.co/xCz1DNEUyt… https://t.co/XCb6gH4OvX https://t.co/fcRxw2gtFt
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Mashup Score: 3Carvedilol Activates a Myofilament Signaling Circuitry to Restore Cardiac Contractility in Heart Failure: - 5 month(s) ago
Highlights •Carvedilol induces β1AR coupling to NOS3 to promote myofilament PKG1 signaling.•Myofilament PKG1 promotes the phosphorylation of MYPT1 and MLC.•The myofilament PKG1 enhances EC coupling…
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Dr. Ying Wang, et al. describe novel evidence for a pathway linking carvedilol to enhanced myocardial PKG1 signaling via B1AR coupling to NOS3. This has important implications for mechanisms to enhance contractility in ischemic heart failure. https://t.co/nwS2H3Ncan #JACCBTS… https://t.co/x9TtxiK3qc https://t.co/43EWtZjB0f
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Stability of of ready-to-use solutions of acetylcholine for intracoronary provocative testing Read the new #JACCBTS research letter by Drs. Sylvia K. Neef, Peter Ong, & colleagues: https://t.co/677Gg8Inwg https://t.co/EMexvGvvkI