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Mashup Score: 0
Two or more negative tests could suggest less need for colonoscopy at 5 years, especially in those with a family history of colon cancer.
Source: www.mdedge.comCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 1
Immunotherapy including immune checkpoint inhibitors (ICIs) has become the backbone of treatment for most lung cancers with advanced or metastatic disease. In addition, they have increasingly been used for early stage tumors in neoadjuvant and adjuvant settings. Unfortunately, however, only a subset of patients experiences meaningful response to ICIs. Although programmed death-ligand 1 (PD-L1)…
Source: Journal of Thoracic OncologyCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
This @IASLC Pathology Committee review provides an overview of various immunotherapy biomarkers incl. updated data on #PD-L1 IHC and TMB to underline the efficacy of new individual or combined predictive biomarkers beyond PD-L1 #IHC and #TMB. https://t.co/nYkOylhsCo #LCSM https://t.co/PIzOIjneMh
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Mashup Score: 1Deficiency of MicroRNA-181a Results in Transcriptome-Wide Cell-Specific Changes in the Kidney and Increases Blood Pressure - 3 year(s) ago
MicroRNA miR-181a is downregulated in the kidneys of hypertensive patients and hypertensive mice. In vitro, miR-181a is a posttranslational inhibitor of renin expression, but pleiotropic mechanisms b
Source: HypertensionCategories: Cardiology News and Journals, Latest HeadlinesTweet-
This study led by @FZMarques and @GeoffreyHead combines a new #CRISPR_Cas9 model #RNAScope @ACDbio and #scRNA_seq technology with traditional techniques such as telemetry and #renin #IHC to describe how #miR181a regulates #BloodPressure #MicroRNA #SSBP. https://t.co/AmjN6duS2C https://t.co/jmCqTDgiVI
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Mashup Score: 0
Anal high-grade squamous intraepithelial lesions (HSILs) constitute a heterogeneous group of precancerous lesions. Understanding which HSILs progress to cancer could facilitate early detection and tr…
Source: Wiley Online LibraryCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
NOW ONLINE | New #openaccess study by Ramon van der Zee, et al. Authors evaluated the prognostic value of expression of the #IHC markers #p16, Ki-67, and #HPV-E4 in anal tissues with evidence of #precancerous lesions. ➡️https://t.co/Lk8RL8jfL5 #HIV #AnalCancer @amsterdamumc https://t.co/hQ7mv3QJBp
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Mashup Score: 3Gene of the month: FH - 3 year(s) ago
Fumarate hydratase (FH), encoded by the FH gene, is an enzyme which catalyses the conversion of fumarate to L-malate as part of the tricarboxylic acid cycle. Biallelic germline mutations in FH result in fumaric aciduria, a metabolic disorder resulting in severe neurological and developmental abnormalities. Heterozygous germline mutations in FH result in hereditary leiomyomatosis and renal cell…
Source: Journal of Clinical PathologyCategories: Latest Headlines, PathologyTweet-
#GoM 🧬 Explore our brand new Gene of the month issue on Fumarate hydratase (FH), by Zyla and Hodgson 🔬 #molpath #IHC #GUpath https://t.co/8IXsMl88sm https://t.co/7Hf5rOgwdK
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Mashup Score: 2
Aims Low-grade oncocytic tumour (LOT) has recently been introduced as a potential distinct entity. Methods At the Indiana University department of pathology, primary renal epithelial neoplasms between 2005 and 2020 were searched after appropriate institutional review board permissions. Results Twenty-three cases (male/female ratio 14/9) with a median age of 66 (23–84 years) were identified. The…
Source: Journal of Clinical PathologyCategories: General Medicine Journals and Societies, Latest HeadlinesTweet-
#OriginalResearch "Low-grade oncocytic tumour expands the spectrum of renal oncocytic tumours and deserves separate classification: a review of 23 cases from a single tertiary institute" by Akgul et al. #GUpath #surgpath #pathology #IHC 👉https://t.co/yK8pVgVsos https://t.co/lx9je0XgEF
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Mashup Score: 2An Algorithmic Immunohistochemical Approach to Define Tumor Type and Assign Site of Origin - PubMed - 4 year(s) ago
Immunohistochemistry represents an indispensable complement to an epidemiology and morphology-driven approach to tumor diagnosis and site of origin assignment. This review reflects the state of my current practice, based on 15-years’ experience in Pathology and a deep-dive into the literature, alway …
Source: PubMedCategories: Hem/OncsTweet-
RT @sam_albadri: Approaching to tumor diagnosis by using IHC. Great article by @IHC_guy 👍👍https://t.co/DDOEIQBTsj @MayoClinicPath #IHC #pa…
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Interval FITs could cut #Colonoscopies in those at above-average risk 👉https://t.co/84qzdNIirE @MDedgeHemOnc @JimKling #IHC https://t.co/aqAyHLFui3