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    article - 7 month(s) ago

    NewsOncology Times45(S10):p 3, May 20, 2023. | DOI: 10.1097/01.COT.0000936928.77325.9bChronic Lymphocytic LeukemiaChronic Lymphocytic LeukemiaAbout one-third of patients with advanced chronic lymphocytic leukemia (CLL) treated with the targeted drug ibrutinib do not carry two mutated genes commonly associated with relapse, according to an international study published in Blood Advances (2023;…

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    • About one-third of patients with advanced #ChronicLymphocyticLeukemia (CLL) treated with the targeted drug #ibrutinib do not carry two mutated genes commonly associated with #relapse, according to a study published in Blood Advances. https://t.co/HBLxoK0bCz #ThisIsBloodCancer https://t.co/u8e0YB3kJ1

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    article - 7 month(s) ago

    NewsOncology Times45(S10):p 3, May 20, 2023. | DOI: 10.1097/01.COT.0000936928.77325.9bChronic Lymphocytic LeukemiaChronic Lymphocytic LeukemiaAbout one-third of patients with advanced chronic lymphocytic leukemia (CLL) treated with the targeted drug ibrutinib do not carry two mutated genes commonly associated with relapse, according to an international study published in Blood Advances (2023;…

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    • Ibrutinib, which targets BTK, has been highly effective in treating #CLL patients. Despite its success, about 6% of CLL patients develop resistance to or #relapse within 6-12 months of starting #ibrutinib, and an additional 14% do so within 2 years. https://t.co/h7hqZWxzgn https://t.co/OxVFtHSG68

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    Barbara Eichhorst, MD Professor of Medicine at UNIVERSITÄTSKLINIKUM KÖLN, is the author of this OncologyTube.com video. Timestamps: 0:09 Can you tell us about the CELL Trial and it´s design and any significant data. 3:04 How many patients were enrolled in the study and what were the characteristics o…

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    • 🧪 Phase 3 trial aims to replace standard chemo with targeted combos (#Venetoclax #Ibrutinib) + anti-CD20 antibodies in mutation-lacking #CLL patients. Join Barbara Eichhorst, MD @UKKoeln in this [video] https://t.co/YmMPLFvviB. #Leukemia https://t.co/BqmyLy7vNg