• Mashup Score: 4

    2022 was a year of groundbreaking scientific advances for the heart failure (HF) community at large. Several landmark trials were presented and/or published that will have a significant impact on clinical practice. As we reflect on this productive year, we wanted to take the opportunity to summarize key results for some of these practice-changing trials, while highlighting important initiatives…

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    • What year 2022 was in #FunctionNotFailure!! Check out our @JCardFail January Ed page led by @vbluml summarizing 🔑 trials in our field & specific JCF papers & initiatives!Looking forward to innovation & discovery in 2023! @robmentz https://t.co/VCySSnfQrF https://t.co/Zc0mnbrPNT https://t.co/Qasj95ipAq

  • Mashup Score: 8

    The Food and Drug Administration (FDA) is required to make decisions that can at times be controversial, for a myriad of reasons, on the benefits versus risks for medical products. This is understandable as science accelerates but with a suboptimal or more complex evidence generation system. For guidance on some of these decisions, the FDA occasionally asks an advisory committee to weigh in on…

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    • Unique 💡insight from @texhern @DCRINews as to @US_FDA advisory board decision on #OmecamtivMecarbil & opportunities that lie ahead👇🏽 As always @JCardFail strives to be your home for all things #FunctionNotFailure promoting constructive discourse 🗣️ https://t.co/iiJTs1RfR7 https://t.co/wadMmi3IHW https://t.co/tgnq52WhvQ

  • Mashup Score: 11

    The monitoring and treatment of congestion are key pillars of modern heart failure (HF) management. Intravascular volume derangement in HF is a well-recognized problem; however, the routine assessment of congestion poses challenges in clinical practice as the signs and symptoms are neither sensitive nor specific.1 In fact, no commonly used surrogate of volume status (ie, physical signs,…

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    • Brilliant thread 👇🏽@FudimMarat ♦️Pressure does not always🟰volume! ♦️“Decongestion” is not always achieved w/diuretics alone!! 🙌🏽Think #GDMTworks & vasodilation too! #FunctionNotFailure https://t.co/8mNiylPR6i https://t.co/fJNbCYVVZl https://t.co/zzyS09e2Gi

  • Mashup Score: 8

    The 1912 Nobel prize in Medicine and Physiology was given to Alexis Carrel for his work on the anastomosis of blood vessels, which formed the basis for organ transplantation. It is claimed he prophesied that “the ideal method would be to transplant in man organs of animals easy to secure and operate on, such as hogs, for instance. But it would in all probability be necessary to immunize organs of…

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    • One stop 🛑shop for 🔥topic : donation after circulatory death w/recent article in @nytimes to this effect also!!! The field of 🫀#transplant is stagnant no longer…#FunctionNotFailure Also ICYMI: 👀check out https://t.co/1o10hxS2Ag on #xenotransplant @MRMehraMD https://t.co/gfSFEhIHY5 https://t.co/a6wrvreJ7y

  • Mashup Score: 12

    Abstract Background There are currently limited accurate national estimates for pediatric heart failure (HF). Objectives This study aims to describe the current burden of primary and comorbid pedia…

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    • Important work now out in #JACC on the rising burden of pediatric #heartfailure in the United States. Check out Drs. @ShaanAmdani, @WilsonTangMD, and colleagues paper in JACC to learn more: https://t.co/vnydpfkMfC #FunctionNotFailure #MedEd #cvPed #CardioTwitter https://t.co/5MVVONsDMD