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    • #ENZAMET shows 60% increase in OS / incr 3 yr OS from 83% to 92% at 33 months follow-up for pts with metach low vol mHSPC https://t.co/5YnBdl8jiu Should control arm for SBRT oligomet HSPC trials be? @ANZUPtrials @Uromigos @APCCC_Lugano @DanaFarber_GU @PCF_Science @EUplatinum

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    About ScienceDirectRemote accessShopping cartAdvertiseContact and supportTerms and conditionsPrivacy policyWe use cookies to help provide and enhance our service and tailor content and ads. By continuing you agree to the use of cookies.Copyright © 2021 Elsevier B.V. or its licensors or contributors. ScienceDirect ® is a registered trademark of Elsevier B.V.

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    • ... continued 4) is #3 / SBRT "reasonable" with incr 3y OS from 83% to 92% for metach low vol with enzalutimde in #ENZAMET and supported by apalutamide #TITAN @ANZUPtrials @APCCC_Lugano @Prof_IanD @Uromigos @scserendipity1 @DanaFarber_GU @neerajaiims https://t.co/5YnBdl8jiu https://t.co/iXsX36uqi7

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    This systematic review and network meta-analysis compares the results of randomized clinical trials that evaluated the use of medications used in the treatment of metastatic castration-resistant prostate cancer.

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    • Interesting meta-analysis of mHSPC trials in @JAMAOnc but I think unreasonably hard on enzalutamide: only #ENZAMET had OS as primary endpoint, and was the only one with an active control and allowed concurrent chemo; ARCHES reported OS data were immature. https://t.co/0hwp7OLOJV