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Mashup Score: 41
lity in pediatric patients with LTH while on ECMO. Children who were on ECMO during an LTH were compared to children with LTH who were not on ECMO. Primary outcomes were volumes of blood products administered and 28 day mortality. Comparisons were assessed by two-sided Fisher’s exact test or Wilcoxon rank sum test. A total of 449 children, including 36 on ECMO, were included. Compared to those not on ECMO, children on ECMO received a higher volume of blood products (110 [50–223] vs. 59 [28–113]) ml/kg, p = 0.002) and were more likely to receive antifibrinolytic therapy (39% vs. 10%, p < 0.001). Blood product ratios were similar. Extracorporeal membrane oxygenation patients had higher 28 day mortality (64% vs. 35%, p = 0.001), although 24 hour mortality was similar (17% vs. 23%, p = 0.5). In conclusion, children on ECMO with LTH experience high resource utilization and 28 day mortality. Studies are needed to identify children at risk for LTH and to evaluate ECMO-specific treatment strat
Source: journals.lww.comCategories: General Medicine News, Critical CareTweet
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Mashup Score: 19
the trajectory of functional status in pediatric ECMO survivors. Pediatric ECMO survivors ≥1-year postdecannulation and ≥3 years of age at follow-up were prospectively enrolled and completed assessments of adaptive behavior (Vineland Adaptive Behavior Scales, Third Edition [Vineland-3]) and functional status (Functional Status Scale [FSS]). Patient characteristics were retrospectively collected. Forty-one ECMO survivors cannulated at 0.0–19.8 years (median: 2.4 [IQR: 0.0, 13.1]) were enrolled at 1.3–12.8 years (median: 5.5 [IQR: 3.3, 6.5]) postdecannulation. ECMO survivors scored significantly lower than the normative population in the Vineland-3 Adaptive Behavior Composite (85 [IQR: 70, 99], P < 0.001) and all domains (Communication, Daily Living, Socialization, Motor). Independent risk factors for lower Vineland-3 composite scores included extracorporeal cardiopulmonary resuscitation, electrographic seizures during ECMO, congenital heart disease, and premorbid developmental delay. Of
Source: journals.lww.comCategories: General Medicine News, Critical CareTweet-
Long-term neurobehavioral & functional outcomes of pediatric #ECMO survivors ➡️ most of pts w impaired function at discharge experience recovery at follow-up but mild neurobehavioral impairment may persist years after decannulation @asaiojournal #PedsICU 🔓https://t.co/9n9dQKF46E https://t.co/t4CLt6DHaa
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Children on #ECMO experiencing life-threatening hemorrhage 🩸received higher blood products volume + more likely to receive antifibrinolytics; blood product ratios similar 🪦 had higher 28 day but similar 24h mortality @asaiojournal #PedsICU @PALISInet 🖇️ https://t.co/nLCFQ5EGR9 https://t.co/AdgSn9BNOF