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Mashup Score: 0Nebulized levofloxacin for chronic Burkholderia cenocepacia pulmonary infection in cystic fibrosis: A case report - PubMed - 1 year(s) ago
We present a patient with cystic fibrosis who used nebulized levofloxacin off-label to suppress chronic Burkholderia cenocepacia pulmonary infection. The patient was initially using tobramycin inhalation powder (TIP) off-label continuously for suppression of chronic B. cenocepacia; thi …
Source: PubMedCategories: Latest Headlines, PulmonologyTweet
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Mashup Score: 0Contemporary cystic fibrosis incidence rates in Canada and the United States - PubMed - 1 year(s) ago
Contemporary CF incidence rates suggest CF incidence is lower than previously reported and varies widely within North America. This information is important for resource planning and for tracking how programs (e.g., genetic counselling, modulator availability etc.) may impact the incidence of CF mov …
Source: PubMedCategories: Latest Headlines, PulmonologyTweet
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Mashup Score: 0Rate of Lung Function Decline in People with Cystic Fibrosis Having a Residual Function Gene Mutation - PubMed - 2 year(s) ago
Progressive lung function decline was observed in people with F/RF genotypes across all assessed age groups, reinforcing the importance of early intervention and clinical monitoring to preserve lung function in all people with CF.
Source: PubMedCategories: Critical Care, Latest HeadlinesTweet
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Mashup Score: 0Multicenter prospective study showing a high gastrointestinal symptom burden in cystic fibrosis - PubMed - 2 year(s) ago
GOV: NCT03801993.
Source: PubMedCategories: Latest Headlines, PulmonologyTweet
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Mashup Score: 1Cystic Fibrosis: Highly Effective Targeted Therapeutics and the Impact on Sex and Racial Disparities - PubMed - 2 year(s) ago
People with Cystic Fibrosis (CF) are living longer and healthier lives due in part to new therapies, called Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) modulators. However, disparities in outcomes still exist, with females demonstrating a shorter life expectancy than males; this is op …
Source: PubMedCategories: Latest Headlines, PulmonologyTweet
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Mashup Score: 0
The cystic fibrosis transmembrane conductance regulator (CFTR) anion channel and the epithelial Na+ channel (ENaC) play essential roles in transepithelial ion and fluid transport in numerous epithelial tissues. Inhibitors of both channels have been important tools for defining their physi …
Source: PubMedCategories: Latest Headlines, PulmonologyTweet
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Mashup Score: 0α-Tocopherol Pharmacokinetics in Adults with Cystic Fibrosis: Benefits of Supplemental Vitamin C Administration - 2 year(s) ago
Background: Numerous abnormalities in cystic fibrosis (CF) could influence tocopherol absorption, transportation, storage, metabolism and excretion. We hypothesized that the oxidative distress due to inflammation in CF increases vitamin E utilization, which could be positively influenced by supplemental vitamin C administration. Methods: Immediately before and after receiving vitamin C (500 mg)…
Source: MDPICategories: Latest Headlines, PulmonologyTweet
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Mashup Score: 1
Maintenance treatment with inhaled antibiotic agents has been found to reduce the burden of bacteria in the airways [1–3], as well as the frequency of exacerbations and hospitalizations in people with cystic fibrosis (pwCF) who are chronically infected with Pseudomonas aeruginosa (PA) [1,3–8]. Accordingly, CF practice guidelines recommend chronic treatment with inhaled antibiotics for pwCF who…
Source: Journal of Cystic FibrosisCategories: Latest Headlines, PulmonologyTweet
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Mashup Score: 1
Maintenance treatment with inhaled antibiotic agents has been found to reduce the burden of bacteria in the airways [1–3], as well as the frequency of exacerbations and hospitalizations in people with cystic fibrosis (pwCF) who are chronically infected with Pseudomonas aeruginosa (PA) [1,3–8]. Accordingly, CF practice guidelines recommend chronic treatment with inhaled antibiotics for pwCF who…
Source: Journal of Cystic FibrosisCategories: Latest Headlines, PulmonologyTweet
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Mashup Score: 1
TOT fills a critical gap in preparing people with CF for shared decision-making about LTx and may serve as a model for educational tools for other preference-sensitive decisions.
Source: PubMedCategories: Latest Headlines, PulmonologyTweet
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