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Mashup Score: 0An Indian perspective for umbilical cord blood haematological parameters reference interval - BMC Pediatrics - 2 year(s) ago
Background The Haematological Reference Intervals (RIs) are prone to vary on the basis of various factors such as altitude, age, sex, socioeconomic status, etc. These values play a major role in laboratory data interpretation and determine the necessary clinical treatment. Currently, India has no well–established RI for cord blood haematological parameters of newborns. This study aims to…
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Mashup Score: 0Intracardiac thrombosis after congenital heart disease surgeries in neonates: a report of two cases - BMC Pediatrics - 2 year(s) ago
Background Intracardiac thrombosis (ICT) is a rare complication after the cardiopulmonary surgery for interrupted aortic arch (IAA) or total anomalous pulmonary venous connection (TAPVC) without previous records. There are still no general guidelines regarding as the mechanism or management of postoperative ICT in neonates and younger infants. Case presentation We reported the conservative and…
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Mashup Score: 0
Background Radical or conservative surgical treatment for hepatic Cystic Echinococcosis (hepatic CE) is controversial. We aimed to measure the association between radical surgery (RS) versus conservative surgery (CS) and short-term outcomes in our cohort. Methods Medical records of hepatic CE patients’ demographic, clinical, radiological, operative and postoperative details who underwent surgical…
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Mashup Score: 0
Background No study has reported on the relationship between the vasoactive-inotropic score (VIS) and the prognosis of neonates with a severe congenital diaphragmatic hernia (CDH). This study aimed to identify potential risk factors for mortality in patients with CDH. We calculated the VIS based on the vasoactive drugs used during the perioperative period to investigate the relationship between…
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Mashup Score: 1Recombinant ACE2 protein protects against acute lung injury induced by SARS-CoV-2 spike RBD protein - Critical Care - 3 year(s) ago
Background SARS-CoV-2 infection leads to acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). Both clinical data and animal experiments suggest that the renin–angiotensin system (RAS) is involved in the pathogenesis of SARS-CoV-2-induced ALI. Angiotensin-converting enzyme 2 (ACE2) is the functional receptor for SARS-CoV-2 and a crucial negative regulator of RAS. Recombinant…
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Mashup Score: 0
Introduction Real-world evidence on the timing and efficacy of enteral nutrition (EN) practices in intensive care unit (ICU) patients with circulatory shock is limited. We hypothesized early EN (EEN), as compared to delayed EN (DEN), is associated with improved clinical outcomes in mechanically ventilated (MV) patients with circulatory shock. Methods We analyzed a dataset from an international,…
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Mashup Score: 0Lack of SARS-CoV-2-specific cellular response in critically ill COVID-19 patients despite apparent effective vaccination - Critical Care - 3 year(s) ago
Correspondence Open Access Published: 08 June 2022 Critical Care volume 26, Article number: 170 (2022) Cite this article …
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Mashup Score: 1Resilience is a dirty word: misunderstood, and how we can truly build it - Critical Care - 3 year(s) ago
Resilience is ubiquitous in everyday speech, academic literature and governmental policies. Yet it seems to have taken a narrow scope in healthcare, confined to individual and psychological resilience. This short essay aims to broaden the understanding of resilience to organisational levels and calls intensivists to take active roles in fostering resilience for their staff. The article explores…
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Mashup Score: 3Pentraxin-3 as a predictive marker of mortality in sepsis: an updated systematic review and meta-analysis - Critical Care - 3 year(s) ago
Background The purpose of this study was to clarify the prognostic value of Pentraxin-3 (PTX3) on the mortality of patients with sepsis. Methods Publications published up to January 2021 were retrieved from PubMed, EMBASE, and the Cochrane library. Data from eligible cohort and case–control studies were extracted for the meta-analysis. Multivariate regression analysis was used to evaluate the…
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Mashup Score: 2Intermediate-risk pulmonary embolism: echocardiography predictors of clinical deterioration - Critical Care - 3 year(s) ago
Background We determine the predictive value of transthoracic echocardiographic (TTE) metrics for clinical deterioration within 5 days in adults with intermediate-risk pulmonary embolism (PE). Methods This was a prospective observational study of intermediate-risk PE patients. To determine associations of TTE and clinical predictors with clinical deterioration, we used univariable analysis,…
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