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Mashup Score: 1Unraveling the Impact: The Role of Acute Carotid Stenting in Tandem Lesions on Functional Outcomes — Insights From a Multicenter Registry - 8 hour(s) ago
The retrospective cohort study by Rodriguez Calienes et al. investigated the impact of acute carotid artery stenting (CAS) in patients with tandem lesions (TL) on functional outcomes. TL were characterized by a simultaneous intracranial occlusion and an extracranial steno-occlusive internal carotid artery lesion (> 70% stenosis). These patients present a unique challenge in stroke management, tending to have poorer outcomes than patients with solitary intracranial occlusions. 1 Additionally, the role of
Source: www.ahajournals.orgCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 24
Intracranial atherosclerotic stenosis (ICAS) is a progressive disease, despite aggressive medical management. Previous RCTs did not show benefit of percutaneous angioplasty and stenting compared to aggressive medical management, and also showed high rates of periprocedural complications. 1,2,3 The risks of percutaneous angioplasty are theoretically lower — and while cohort studies have suggested acceptable periprocedural risk, comparison of percutaneous angioplasty versus aggressive medical management
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Mashup Score: 40Antithrombotic Therapy For Cancer-Associated Stroke: Does ARCADIA Help Resolve the Equipoise? - 13 day(s) ago
People with cancer have an increased risk of arterial thromboembolism that peaks within the first few months following diagnosis, when cancer is most active and generates variable degrees of systemic hypercoagulability. This cancer-related hypercoagulable state likely contributes at least partly to most ischemic strokes in people with active cancer, as supported by the presence of markers of upregulated coagulation activity such as elevated d-dimers and the high prevalence of embolic stroke of undetermined
Source: www.ahajournals.orgCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 55Article Commentary: “Anticoagulants versus Antiplatelet Treatment in the Medical Management of Carotid Floating Thrombus” - 2 month(s) ago
Carotid floating thrombus (CFT) is a rare but serious variant of intraluminal thrombus that is attached to the luminal side of the vessel at one end and free at the other end. This can present as an emergency due to the inherent risk of dislodgement and embolization causing recurrent stroke. Unfortunately, there is no consensus regarding the management of the same owing to the very small incidence in about 1.6% of all strokes. Many neurologists treat it with varying combinations of antiplatelets and
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Mashup Score: 6
An interview with Dr. Yi Yang, MD, PhD, Professor of Neurology at the University of New Mexico School of Medicine. Interviewed by Dr. Hansen Chen, PhD, Instructor, Department of Neurosu rgery, School of Medicine, Stanford University. Dr. Chen: Hello, Dr. Yang, it is a pleasure to have you with us at Blogging Stroke. We are excited to discuss your recent publication, “Progressive Disruption of Sphingosine-1-Phosphate Receptor 1 Correlates with Blood-Brain Barrier Leakage in A Rat Model of Chronic Hypoxic
Source: www.ahajournals.orgCategories: General Medicine News, CardiologistsTweet-
#BloggingStroke contributor @Chenhsbbb interviews Dr. Yi Yang on “Progressive Disruption of Sphingosine-1-Phosphate Receptor 1 Correlates with Blood-Brain Barrier Leakage in A Rat Model of Chronic Hypoxic Hypoperfusion,” published in Aging and Disease. https://t.co/IwvRcGBEbn https://t.co/ijZvbtXCHe
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Mashup Score: 4Does Semaglutide Increase the Risk of Nonarteritic Anterior Ischemic Optic Neuropathy? - 5 month(s) ago
Glucagon-like peptide-1 receptor agonist (GLP-1 RA) medications have transformed the management of type 2 diabetes and obesity in record time. Semaglutide is a GLP-1 RA first approved by the US Food and Drug Administration (FDA) in 2017 to improve glycemic control in adults with type 2 diabetes and for chronic weight management in adults with obesity or overweight (in the presence of at least one weight-related comorbid condition) and in pediatric patients aged 12 years and older with obesity. 1 Previous
Source: www.ahajournals.orgCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 53Intravenous Thrombolysis in Unknown-Onset Strokes: Should We Differentiate Wake-Up From Non–Wake-Up Unwitnessed Strokes? - 6 month(s) ago
Up to nearly one-third of acute ischemic stroke patients have an unknown symptom onset. These patients may be categorized into two subgroups: wake-up strokes (WUS) and non – wakeup unwitnessed strokes (non-WUS), the latter being daytime-unwitnessed onset strokes where patients are unable to provide details due to aphasia or disturbances in mental status. While MRI-based tissue-clocking and perfusion imaging have guided patient selection, these two subgroups of patients are often combined in analyses.
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#BloggingStroke Intravenous Thrombolysis in Unknown-Onset Strokes: Should We Differentiate Wake-Up From Non–Wake-Up Unwitnessed Strokes? https://t.co/VFFutvoU4Z @dianajyk discusses Stroke article by Kamogawa et al @braindoc_mgh @ProfSteveDavis @warach_steven @sohei_y @mkaori0612 https://t.co/COcDcCdAzC
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Mashup Score: 20Author Interview: Dr. Enrique C. Leira on “Uric Acid: A Translational Journey in Cerebroprotection That Spanned Preclinical and Human Data” - 7 month(s) ago
An interview with Dr. Enrique C. Leira, MD, MS, Stoppelmoor-Adams Professor in Vascular Neurology and Head of the Comprehensive Stroke Center, University of Iowa Carver College of Medicine. Interviewed by Dr. Hansen Chen, PhD, Instructor, Department of Neurosurgery, School of Medicine, Stanford University. Dr. Chen: Hello, Dr. Leira, it’s a pleasure to have you with us at Blogging Stroke. We’re intrigued by your recent publication on the potential of uric acid in stroke treatment. Could you summarize the
Source: www.ahajournals.orgCategories: General Medicine News, Cardiology News and JournTweet
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Mashup Score: 3Endovascular Treatment Without CT-Perfusion Mismatch and the Role of Successful Recanalization on Functional Outcome - 8 month(s) ago
Randomized controlled trials showed that mechanical thrombectomy improved functional outcomes in patients with ischemic stroke selected by CT-perfusion mismatch imaging in the extended time window and is also used to select patients for treatment despite large infarct core volumes. 1-2 Therefore, this advanced imaging is increasingly being applied to guide treatment decisions in acute ischemic stroke using the core-penumbra concept, which is known to be highly predictive of outcome and mortality after
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Mashup Score: 8Article Commentary: “Apixaban to Prevent Recurrence After Cryptogenic Stroke in Patients With Atrial Cardiopathy” - 8 month(s) ago
The ARCADIA trial is a study looking into the role of apixaban in treatment of cryptogenic strokes when patients have evidence of atrial cardiopathy. This was a multicenter, double blind, phase 3 randomized trial involving 1015 patients. Evidence of atrial cardiopathy involved satisfying the criteria defined as P-wave terminal force greater than 5000 μ V × ms in electrocardiogram lead V1, serum N-terminal pro-B-type natriuretic peptide level greater than 250 pg/mL or left atrial diameter index of 3 cm/m2
Source: www.ahajournals.orgCategories: General Medicine News, Cardiology News and JournTweet
Unraveling the Impact: The Role of Acute Carotid Stenting in Tandem Lesions on Functional Outcomes — Insights From a Multicenter Registry In this #BloggingStroke post, Kristina Rankine discusses Neurology article by Rodriguez-Calienes et al. https://t.co/tCJpKrcGEi https://t.co/MiBAkP4I1R