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Mashup Score: 4FLAMBE: A kinetic fluorescence polarization assay to study activation of monomeric BAX: STAR Protocols - 2 year(s) ago
Summary BAX activation techniques are crucial to studying the intrinsic pathway of apoptosis— thousands of pro-apoptotic signals converge on BAX activation. Current methodologies are predominantly limited to membrane permeabilization studies, which assess endpoint functionality of oligomeric BAX, but overlook early activation steps of cytosolic BAX. Here we detail FLAMBE: a fluorescence…
Source: star-protocols.cell.comCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 1Excessive hydrogen sulfide causes lung and brain tissue damage by promoting PARP1/Bax and C9 and inhibiting LAMB1 - PubMed - 2 year(s) ago
Excessive hydrogen sulfide (H2S) causes serious damage to human organs and tissues. In this study, we aimed to explore the role and underlying mechanism of excessive H2S in brain and lung tissues. A H2S concentration of 100-800 pm promotes apoptosis and inflammation …
Source: PubMedCategories: Latest Headlines, PulmonologyTweet-
Excessive #hydrogen #sulfide causes #lung and #brain #tissue damage by promoting #PARP1/ #Bax and #C9 and inhibiting #LAMB1 https://t.co/SBI7iPPxPq https://t.co/vWxMzOptze
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Online in @STARProtocols: Dr. Jerry Edward Chipuk's lab @jarviermohammed @icahnmountsinai @tischcancer describing FLAMBE, a fluorescence polarization assay to detect activation of recombinant #BAX: https://t.co/60kUcdpsJE https://t.co/67CjKdUVfx