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Mashup Score: 0Anti-amyloid antibody therapies in Alzheimer’s disease - 1 year(s) ago
Perneczky et al. examine why previous trials of disease-modifying treatments for Alzheimer’s disease failed and why lecanemab fared differently. They discuss wh
Source: OUP AcademicCategories: Healthcare Professionals, Latest HeadlinesTweet
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Mashup Score: 4
AbstractAims. Atrial fibrillation (AF) occurs in as many as 70% of patients with transthyretin cardiac amyloidosis (ATTR CA). The aim of our study was to invest
Source: OUP AcademicCategories: Cardiologists, Latest HeadlinesTweet-
Wael Jaber with reminders that in patients with ATTR #amyloid #AFib #ablation outcome is dependent upon stage of amyloid - later stages do worse/have more recurrence (90% at Stage III) 📖 from @EoinDonnellan1 https://t.co/IUfGiaazOu #WAFib2023 https://t.co/ha0MWUyEUw
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Mashup Score: 0The Amyloidosis Weekly - 1 year(s) ago
A selection of articles, blog posts, videos and photos recommended by Robert Z. Orlowski
Source: paper.liCategories: Hem/Oncs, Latest HeadlinesTweet-
The latest The Amyloidosis Weekly! https://t.co/tmOWOvRco2 Thanks to @EdwardARowe1 @ISA_Amyloidosis #amyloidosis #amyloid
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Mashup Score: 0Longitudinal Cognitive Decline in Preclinical Alzheimer Disease Using Plasma Biomarkers - 1 year(s) ago
This prognostic study uses data from the Swedish BioFINDER-1 and Wisconsin Registry for Alzheimer Prevention longitudinal cohort studies to evaluate whether combinations of different plasma biomarkers can predict cognitive decline in cognitively unimpaired individuals with β-amyloid positivity.
Source: jamanetwork.comCategories: Healthcare Professionals, Latest HeadlinesTweet-
Question Can plasma biomarkers predict cognitive decline in preclinical #Alzheimer disease (AD)? Longitudinal Cognitive Decline in Preclinical Alzheimer Disease Using #Plasma #Biomarkers: #Ptau217 https://t.co/jGrIAwT6Cs via @JAMANeuro part of @JAMANetwork #amyloid #Aβ
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Mashup Score: 6Plasma Amyloid-β in Relation to Cardiac Function and Risk of Heart Failure in General Population: - 1 year(s) ago
Abstract Background Amyloid-β (Aβ) may be related to cardiac function. However, there are limited data on the association of plasma Aβ with cardiac function and risk of heart failure (HF) in the ge…
Source: JACC: Heart FailureCategories: Expert Picks, Latest HeadlinesTweet-
New in #JACCHF: Plasma amyloid-β is associated with higher risks of myocardial dysfunction and new onset heart failure. https://t.co/8sk7vcb990 #Amyloid #HF #HeartFailure #MyocardialDysfunction #CardioTwitter https://t.co/XmWllFR0ak
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Mashup Score: 0
Researchers examined longitudinal changes in CSF Alzheimer disease biomarker among patients with normal cognition over an 11-year follow-up, on average.
Source: Neurology AdvisorCategories: Latest Headlines, NeurologyTweet-
Several years before the onset of clinical symptoms of #Alzheimer disease changes in #amyloid and tau levels occur. #NeuroTwitter https://t.co/AAWrPTCLVP
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Mashup Score: 4
AbstractBackground. Transthyretin amyloid cardiomyopathy (ATTR-CM) is usually characterized by left ventricular (LV) hypertrophy or LV systolic dysfunction. How
Source: OUP AcademicCategories: Cardiology News and Journals, Latest HeadlinesTweet-
Severe functional TR due to wild-type transthyretin #amyloid cardiomyopathy without LV hypertrophy https://t.co/IeM1DOIHO2 #EHJCaseReports #WhyCMR #EchoFirst @aayshacader @ANazmiCalik @KardiologieHH @EHJCREiC @TJ_Yeo @cfcamm @FarhanaAra https://t.co/agIJBqjPMf
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Mashup Score: 1Extracellular Volume Fraction by Computed Tomography Predicts Long-Term Prognosis Among Patients With Cardiac Amyloidosis: - 1 year(s) ago
Abstract Background Light chain (AL) and transthyretin (ATTR) amyloid fibrils are deposited in the extracellular space of the myocardium, resulting in heart failure and premature mortality. Extrace…
Source: JACC: Cardiovascular ImagingCategories: Expert Picks, Latest HeadlinesTweet-
Cardiac #amyloid burden quantified by #yesCCT ECVCT correlates with adverse remodeling & all-cause long-term mortality in #ATTR patients. https://t.co/edPXl6yFKb #JACCIMG #cvImaging #Amyloidosis #CardioTwitter @ThomasTreibel https://t.co/Rgw3hxEiVh
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Mashup Score: 1Imaging As Surrogate Endpoints - 11/18/22 - 2 year(s) ago
Exploring how imaging is being used in AL/ATTR amyloidosis and identifying challenges to use as endpoints in interventional clinical trials
Source: The Amyloidosis ForumCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
It's critical we connect changes seen in #amyloid imaging to changes in cardiac events, functional measures, & health-related quality of life. @awechalekar and @BrettSperryMD will guide our discussion at the #AmyloidosisForum. Register today: https://t.co/zdFhgHIeRP https://t.co/QMEylxtA1N
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Mashup Score: 0CRISPR/Cas9-based gene editing in patients with transthyretin amyloidosis with cardiomyopathy - PACE-CME - 2 year(s) ago
**AHA 2022** A phase I study investigated the safety, pharmacokinetics, and pharmacodynamics of NTLA-2001, a CRISPR/Cas9-based in vivo gene editing therapy, in patients with transthyretin amyloidosis with cardiomyopathy.
Source: PACE-CMECategories: Cardiologists, Latest HeadlinesTweet-
CRISPR/Cas9-based gene editing in patients with transthyretin amyloidosis with cardiomyopathy - PACE-CME #CRISPR #amyloid #cardiotwitter https://t.co/J5ra3xZVLx
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Anti-#amyloid antibody therapies in #Alzheimer’s disease https://t.co/qTJi9ua3nj AD, like #ChronicPain, may require a combination of drugs targeting different biological mechanisms. https://t.co/j2FVMJ9rkr