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Mashup Score: 0Ann Zauber and Sidney Winawer on CRC Screening Approaches - 7 month(s) ago
Colorectal cancer (CRC) screening is becoming more important as disease is being detected in concerning numbers among individuals under age 50. Current guidelines recommend screening colonoscopy and sequential high-sensitivity fecal occult blood testing (HSgFOBT).
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Mashup Score: 0Janice Oh on the Surprising Prevalence of Abdominal Bloating - 7 month(s) ago
Abdominal bloating is a common symptom, especially in patients with disorders of gut-brain interaction, but comparatively little is known about its actual prevalence and clinical impact on the general population. Bloating remains incompletely understood with regard to pathophysiology and treatment options.
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Mashup Score: 1Heather Armstrong on How Some Dietary Fibers Worsen IBD - 8 month(s) ago
Inflammatory bowel diseases (IBD) are affected by dietary factors, including nondigestible carbohydrates fermented by colonic microbes. While fiber consumption is beneficial overall, not all fibers are alike and some IBD patients report intolerance to fiber consumption.
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Mashup Score: 0
Irritable bowel syndrome (IBS) is a gut-brain pain disorder that is classified according to bowel habits, even though non-gastrointestinal factors may influence clinical course and outcomes. In light of this discrepancy, Madhusudan Grover, MD, of the Mayo Clinic in Rochester, Minnesota, and colleagues conducted a survey-based case-control study to determine if IBS patients cluster according to various parameters, including clinical, dietary, lifestyle, and psychosocial factors.
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Mashup Score: 1
Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality worldwide, and incidence rates are At advanced unresectable stages, when only systemic therapies are effective, outcomes remain dismal. Until recently, treatment was dominated by tyrosine kinase inhibitors (TKIs) such as sorafenib (Nexavar) and lenvatinib (Lenvima), but these have conferred only a marginal improvement in survival for the majority of patients.
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Mashup Score: 2Floris de Voogd on Intestinal Ultrasound for Tracking Response in UC - 8 month(s) ago
While endoscopy is the gold standard for assessing treatment response and remission in ulcerative colitis (UC), intestinal ultrasound (IUS) has been proposed as a faster, noninvasive, and less costly alternative. Recently, a group led by Floris de Voogd, MD, of Amsterdam University Medical Center in the Netherlands, evaluated IUS against endoscopy for monitoring patients with moderate to severe UC.
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Mashup Score: 0Archita Desai on a New Tool to Monitor Cirrhosis Patients - 9 month(s) ago
Liver cirrhosis imposes a growing economic burden on the U.S. .
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Mashup Score: 0
About a third of patients with primary biliary cholangitis (PBC) do not respond to first-line therapy with ursodeoxycholic acid (UDCA). Second-line treatment entails either obeticholic acid (OCA) or fibric acid derivatives (bezafibrate or fenofibrate), but data comparing the effectiveness of the two treatments have been sparse.
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Mashup Score: 0Gili Focht on a New Tool for Assessing Pediatric Crohn's Disease - 9 month(s) ago
Crohn’s disease (CD) is often more extensive in children compared with adults and requires a tool using magnetic resonance enterography (MRE) for assessing inflammation in the entire bowel. To that end, Gili Focht, MSc, MBA, of the Juliet Keidan Institute of Pediatric Gastroenterology, Hepatology, and Nutrition at the Hebrew University of Jerusalem, and an international team of researchers developed and validated the Pediatric Inflammatory Crohn’s Magnetic Resonance Enterography Index (PICMI), which evaluates transmural inflammation in all segments of the intestine and without the use of rectal contrast agents.
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Mashup Score: 0Cesare Hassan on Using AI for Detecting Colorectal Polyps - 9 month(s) ago
There’s a growing need for cost-saving strategies that allow for optically diagnosing colorectal polyps in order to reduce the patient, economic, and environmental burden of polypectomy and pathology. One recommendation has been to adopt a leave-in-situ approach for small, non-threatening rectosigmoid hyperplastic polyps ≤5 mm and a resect-and-discard approach for more proximal lesions ≤5 mm.
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ICYMI: What are the immediate clinical implications for colorectal cancer screening here? #AGAReadingRoom @AmerGastroAssn #Gastroenterology Read more: https://t.co/zrnWXW4709 https://t.co/b7TWaab04p