Stroke Literature Synopses (Preclinical) | Stroke
Ischemic strokes can be associated with continued infarction of various brain regions, may lead to transient or lasting cognitive deficits, and are prone to recurrence. However, the role of inflammation has remained elusive in the context of the progression of ischemic strokes and their sequelae. The following publications provide evidence of how AIM2 (absent in melanoma 2), the inflammasome, and double-stranded DNA (dsDNA) sensing contribute to the aforementioned process. Most importantly, the mechanisms
