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Mashup Score: 2
Mariana Brandao, MD, PhD, Institute Jules Bordet, Brussels, Belgium, delves into the complexities of defining operability in non-small cell lung cancer (NSCLC), acknowledging the unique challenges posed by the necessity of the lungs for survival. She outlines three key factors in assessing operability: oncological operability, focusing on the potential for surgery to improve cure rates compared to other treatments; functional operability, which involves evaluating patient comorbidities and assessing cardiac and pulmonary function to determine surgical tolerance; and technical operability, based on anatomical criteria such as tumor size, location, and relation to adjacent structures, aiming for clear pathological margins. Dr Brandao emphasizes the challenges posed by stage three disease, characterized by heterogeneous tumor characteristics and varying degrees of lymph node involvement, which can complicate surgical decision-making. This interview took place at the BTOG 2024 congress in
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Mashup Score: 1Lung cancer initiation: towards molecular cancer prevention - 2 day(s) ago
Charles Swanton, Francis Crick Institute in London, discusses his research on the initiation and progression of lung cancer in response to air pollution exposure. Focusing on non-small cell lung cancer (NSCLC) in never smokers, Prof. Swanton presents findings from mouse models and human epidemiology datasets, revealing a link between air pollution and increased tumor formation. He proposes that air pollutants trigger an inflammatory response mediated by macrophages, leading to the transformation of preexisting lung stem cells into tumors. Prof. Swanton explores the role of myeloid cells in cancer initiation and progression, highlighting the significance of clonal hematopoiesis of indeterminate potential (CHIP). This interview took place at the BTOG 2024 congress in Belfast, UK. These works are owned by Magdalen Medical Publishing (MMP) and are protected by copyright laws and treaties around the world. All rights are reserved.
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Mashup Score: 0VJOncology – The video journal of oncology - 3 day(s) ago
The Video Journal of Oncology (VJOncology) is an independent, global, open-access video journal, dedicated to providing trusted and up-to-date information in order to improve the awareness and understanding of oncology
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Mashup Score: 2CHRYSALIS: amivantamab in wild-type, pre-treated NSCLC - 5 day(s) ago
Natasha Leighl, MD, University of Toronto, Toronto, Canada, discusses findings from the Phase Ib CHRYSALIS trial (NCT02609776) of amivantamab, an EGFR-MET bispecific antibody, in patients with wild-type non-small cell lung cancer (NSCLC) who have progressed on checkpoint inhibition and chemotherapy. Two cohorts consisting of patients with either adenocarcinomas or squamous lung cancer were recruited, and responses were reported in both cohorts, but patients with KRAS or HER2 mutations did not respond to therapy. This interview took place at American Association for Cancer Research (AACR) Annual Meeting 2024 in San Diego, CA. These works are owned by Magdalen Medical Publishing (MMP) and are protected by copyright laws and treaties around the world. All rights are reserved.
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Mashup Score: 1
Tatsuhiro Shibata, PhD, University of Tokyo, Tokyo, Japan, comments on emerging biomolecular therapeutic targets for the treatment of patients with gastric and gastroesophageal cancers. Promising biomarker targets include epidermal growth factor receptor 2 (EGFR2), claudins, and ones for immune checkpoint inhibitors (ICI). Prof. Shibata emphasizes that his session is being delivered at an opportune time, given the current state of scientific research on potential treatments for gastroesophageal cancer. This interview took place at the 2024 American Association for Cancer Research (AACR) in San Diego, CA. These works are owned by Magdalen Medical Publishing (MMP) and are protected by copyright laws and treaties around the world. All rights are reserved.
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Mashup Score: 6BTOG 2024 insights & future directions: a comprehensive approach to thoracic malignancies - 9 day(s) ago
Sanjay Popat, from The Royal Marsden NHS Foundation Trust in London, UK, shares his enthusiasm for the BTOG 2024 congress in Belfast, UK, which gathered over a thousand delegates. The meeting emphasized the comprehensive approach to managing primary thoracic malignancies, with representation from various disciplines including respiratory physicians, medical oncologists, surgeons, and more. Prof. Popat highlights BTOG’s commitment to providing equitable and optimal care through education, research, facilitation, and representation. He encourages registration for membership, offering access to CPD accredited educational materials and specialist events. The upcoming agenda includes webinars updating on international meetings outcomes and essential updates on mesothelioma and stage IV malignancies treatment paradigms. Notably, BTOG introduces a research group to foster structured academic drug trials research. Prof. Popat looks forward to reconvening at BTOG 2025 for another enriching meet
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Mashup Score: 0VJOncology – The video journal of oncology - 9 day(s) ago
The Video Journal of Oncology (VJOncology) is an independent, global, open-access video journal, dedicated to providing trusted and up-to-date information in order to improve the awareness and understanding of oncology
Source: www.vjoncology.comCategories: General Medicine News, Onc News and JournalsTweet
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Mashup Score: 0VJOncology – The video journal of oncology - 9 day(s) ago
The Video Journal of Oncology (VJOncology) is an independent, global, open-access video journal, dedicated to providing trusted and up-to-date information in order to improve the awareness and understanding of oncology
Source: www.vjoncology.comCategories: General Medicine News, Onc News and JournalsTweet
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Mashup Score: 0What are some remaining challenges in testicular cancer? - 9 day(s) ago
Ciara Conduit, FRACP, MBBS, PGCert MEd, Peter MacCallum Cancer Centre, Melbourne, Australia, discusses unmet needs in testicular cancer, including mental health issues such as stress and anxiety as a result of diagnosis. More support is required for patients who need it, especially when suicide rates are higher in this population. Novel biomarkers such as microRNAs (miRNAs) are additionally under investigation, where they will be useful for patients who have tumors that may not be able to be easily biopsied. This interview took place at the Australian and New Zealand Urogenital and Prostate (ANZUP) Cancer Trials Group annual scientific meeting in Melbourne, Australia. These works are owned by Magdalen Medical Publishing (MMP) and are protected by copyright laws and treaties around the world. All rights are reserved.
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Mashup Score: 0VJOncology – The video journal of oncology - 10 day(s) ago
The Video Journal of Oncology (VJOncology) is an independent, global, open-access video journal, dedicated to providing trusted and up-to-date information in order to improve the awareness and understanding of oncology
Source: www.vjoncology.comCategories: General Medicine News, Onc News and JournalsTweet
🎥@MarianaBrandao0 of @JulesBordet highlights the multifaceted considerations in defining operability for #NSCLC, shedding light on the challenges posed by stage III disease: ➡️https://t.co/JlkUYGVezy⬅️ @BTOGORG #BTOG24 #LungCancer #LCSM