• Mashup Score: 2
    VAM-IHCA - 3 year(s) ago

    Effect of Vasopressin and Methylprednisolone vs Placebo on Return of Spontaneous Circulation in Patients With In-Hospital Cardiac Arrest: A Randomized Clinical Trial Anderson et al. JAMA 2021. doi:10.1001/jama.2021.16628 Clinical Question In adult patients suffering an in-hospital cardiac arrest (IHCA) does the use of vasopressin and methylprednisolone compared to a placebo result in increased…

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    • RT @cgraydoc: @hgmwalker89 has also reviewed the paper for @WICSBottomLine https://t.co/rPrbynGRXp #VAMIHCAtrial #CCR22

  • Mashup Score: 4
    SETPOINT2 - 3 year(s) ago

    In patients with severe stroke does early (≤5 days of intubation) tracheostomy when compared to standard timing (from day 10) of tracheostomy improve functional outcome at 6 months?

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    • RT @WICSBottomLine: #TBL 410: SETPOINT2 - RCT: Early vs Standard Tracheostomy Among Patients With Severe Stroke https://t.co/3zbO5RDCTV Art…

  • Mashup Score: 1
    Prague OHCA - 3 year(s) ago

    In patients with a witnessed refractory out-of-hospital cardiac arrest (OHCA) does early intra-arrest transport, extracorporeal CPR (ECPR) and invasive assessment improve neurological outcome at 180 days?

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    • @JanBelohlavek the Prague trial showed no difference in outcomes with a hyperinvasive approach to OOHCA (nice @WICSBottomLine review here https://t.co/zNg6AR3pxc) But was it an ECPR trial? #EuroELSO2022

  • Mashup Score: 1
    CONTROLING - 3 year(s) ago

    Individualised versus conventional glucose control in critically-ill patients: the CONTROLING study—a randomized clinical trial Bohé. Intensive Care Medicine 2021. https://doi.org/10.1007/s00134-021-06526-8 Clinical Question In critically unwell adults does targeting individualised glycaemic control compared to glycaemia < 180 mg/dL improve 90 day mortality? Background Hyperglycaemia has been...

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    • RT @cathymac40: CONTROLING – The Bottom Line . Great summary thank you ⁦@TheBottomLine⁩ https://t.co/9ojXhNgnYD

  • Mashup Score: 4
    SNOCAT - 3 year(s) ago

    Effect of Out-of-Hospital Sodium Nitrite on Survival to Hospital Admission After Cardiac Arrest: A Randomized Clinical Trial Kim @uwcardiology. JAMA. 2021 January 12;325(2):138-145. doi: 10.1001/jama.2020.24326. Clinical Question In patients with out-of-hospital cardiac arrest, does sodium nitrite, compared with placebo, improve survival to hospital admission? Background Out-of-hospital cardiac…

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    • RT @WICSBottomLine: #TBL 394: SNOCAT - Sodium Nitrite for Out-Of-Hospital Cardiac Arrest https://t.co/E5vO7wrlLf Article by Kim @UWCardiolo…

  • Mashup Score: 4
    The Bottom Line - 3 year(s) ago

    A compendium of critical appraisals in Intensive Care Medicine research and related specialties

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    • RT @stevemathieu75: Monthly @WICSBottomLine update - latest trials in Critical Care Visit https://t.co/quHntWNzwc for summary of trials.…

  • Mashup Score: 3
    DOREMI - 3 year(s) ago

    Milrinone as compared with Dobutamine in the Treatment of Cardiogenic Shock  Matthew. N Engl J Med 2021; 385:516-525, doi: 10.1056/NEJMoa2026845 Clinical Question In patients with cardiogenic shock, does milrinone as compared with dobutamine improve the composite outcome of in-hospital death, resuscitated cardiac arrest, receipt of cardiac transplant or mechanical circulatory support, non-fatal…

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    • RT @WICSBottomLine: #TBL 386: DoReMi - Milrinone vs Dobutamine for Cardiogenic Shock https://t.co/dbO3cldgto Article by @rebeccamathewmd R…