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Mashup Score: 6SAHARA – Liberal vs Restrictive Transfusion Targets in SAH - 21 day(s) ago
Liberal versus Restrictive Transfusion in Aneurysmal Subarachnoid Haemorrhage English S. NEJM 2024 DOI:10.1056/NEJMoa2410962 Clinical Question In patients following acute aneurysmal subarachnoid haemorrhage, does a liberal strategy of blood transfusion compared with a restrictive strategy of blood transfusion reduce unfavourable neurological outcome? SubArachnoid Haemorrhage Red-cell transfusion And Outcome (SAHaRA) Background Anaemia is common following aneurysmal subarachnoid haemorrhage with an incidence of approximately 50% incidence during…
Source: www.thebottomline.org.ukCategories: General Medicine News, Critical CareTweet
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Mashup Score: 9
Early Restrictive vs Liberal Oxygen for Trauma Patients Arleth. JAMA 2024. doi: 10.1001/jama.2024.25786 Clinical Question In adult patients experiencing blunt or penetrating trauma does an early restrictive oxygen strategy compared to a liberal oxygen strategy reduce death and/or major respiratory complications within 30 days? Background ATLS guidelines recommend that all severely injured patients should receive supplemental oxygen in the initial…
Source: www.thebottomline.org.ukCategories: General Medicine News, Critical CareTweet-
RT @WICSBottomLine: #TBL 461: TRAUMOX2 - Early Restrictive vs Liberal Oxygen for Trauma Patients https://t.co/gwZOsfACF0 Article by Arleth…
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Mashup Score: 2Emergency Evidence Updates – November 2024 - 30 day(s) ago
What’s new in the Critical Care literature – monthly updates
Source: www.thebottomline.org.ukCategories: General Medicine News, Hem/OncsTweet-
RT @WICSBottomLine: Emergency Medicine Evidence Based Updates November 2024 https://t.co/vJKp792trm Critical Care Evidence Based Updates…
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Mashup Score: 6Flexible vs Restrictive Visiting in the ICU - 2 month(s) ago
Long-term effects of flexible visitation in the intensive care unit on family members’ mental health: 12-month results from a randomized clinical trial JMB de Souza et al. Intensive Care Med (2024); 50:1614–1621. DOI: 10.1007/s00134-024-07577-3 Clinical Question In family members of intensive care patients, does a flexible visiting policy, compared to a restrictive one, improve the prevalence of depression, anxiety and…
Source: www.thebottomline.org.ukCategories: General Medicine News, Hem/OncsTweet-
RT @WICSBottomLine: #TBL 458: Flexible vs Restrictive Visiting in the ICU https://t.co/Pa76lcZ1cl Article by de Souza Review by Amoah - fin…
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Mashup Score: 6Pupillometry Thresholds for Neuroprognostication - 2 month(s) ago
Validating quantitative pupillometry thresholds for neuroprognostication after out‑of‑hospital cardiac arrest. A predefined substudy of the Blood Pressure and Oxygenations Targets After Cardiac Arrest (BOX)‑trial Nyholm. Intensive Care Med 2024; 50:1484–1495. doi.org/10.1007/s00134-024-07574-6 Clinical Question In adult out-of-hospital cardiac arrest (OHCA) survivors of presumed cardiac cause who are comatose post-admission, do automated pupillometry thresholds of quantitatively assessed pupillary light reflex (qPLR) <…
Source: www.thebottomline.org.ukCategories: General Medicine News, Hem/OncsTweet-
RT @WICSBottomLine: #TBL 459: Pupillometry Thresholds for Neuroprognostication https://t.co/8LV0tb9KaK Article by Nyholm Review by @etomi…
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Mashup Score: 16Quetiapine Versus Haloperidol for Delirium - 2 month(s) ago
Quetiapine Versus Haloperidol in the Management of Hyperactive Delirium: Randomized Controlled Trial Zakhary et al. Neurocritical Care; Oct;41(2):550-557. doi:10.1007/s12028-024-01948-w Clinical Question In critically ill patients with delirium, does quetiapine in comparison to haloperidol, reduce the severity of delirium? Background Delirium affects 30-50% of adult ICU patients Haloperidol is licensed for the treatment of acute delirium in the UK Previous RCTs…
Source: www.thebottomline.org.ukCategories: General Medicine News, Hem/OncsTweet-
RT @WICSBottomLine: #TBL 460: Quetiapine Versus Haloperidol for Delirium https://t.co/8qgpRdaA11 Article by Zakhary Review by @hqva - Win…
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Mashup Score: 13
Extracorporeal Life Support in Infarct-Related Cardiogenic Shock Thiele H. NEJM 2023; Online ahead of print. doi:10.1056/NEJMoa2307227 Clinical Question In patients presenting with acute myocardial infarction complicated by cardiogenic shock undergoing revascularisation, does the early unselected application of extracorporeal life support reduce mortality from any cause at day 30? Background The use of venoarterial extracorporeal membrane oxygenation (VA ECMO), which is…
Source: www.thebottomline.org.ukCategories: General Medicine News, Hem/OncsTweet-
RT @WICSBottomLine: #TBL 439: ECLS-SHOCK - Extracorporeal Life Support in Infarct-Related Cardiogenic Shock https://t.co/vbkOFGPZLU Article…
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Mashup Score: 6PREOXI Trial – Noninvasive Ventilation for Preoxygenation - 6 month(s) ago
In critically ill patients undergoing tracheal intubation does pre-oxygenation with non-invasive ventilation compared with pre-oxygenation with an oxygen mask reduce the incidence of hypoxemia during intubation?
Source: www.thebottomline.org.ukCategories: General Medicine News, Critical CareTweet-
RT @WICSBottomLine: #TBL 454: PREOXI Trial – Noninvasive Ventilation for Preoxygenation https://t.co/JONZFafkEO Article by @KevinGibbsMD…
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Mashup Score: 7PROPHY-VAP: Ceftriaxone to prevent early ventilator-associated pneumonia - 11 month(s) ago
In patients with severe brain injury who require mechanical ventilation, does an early, single dose of ceftriaxone compared with placebo reduce the incidence of early VAP?
Source: www.thebottomline.org.ukCategories: General Medicine News, Critical CareTweet-
RT @WICSBottomLine: #TBL 445: PROPHY-VAP: Ceftriaxone to prevent early ventilator-associated pneumonia https://t.co/rNT0Vwdf0Z Article by @…
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Mashup Score: 7Emergency Evidence Updates – September 2023 - 1 year(s) ago
What’s new in the Critical Care literature – monthly updates
Source: www.thebottomline.org.ukCategories: General Medicine News, Hem/OncsTweet-
RT @WICSBottomLine: Emergency Medicine Evidence Based Updates Setpember 2023 https://t.co/Kj41BCmCFL Critical Care Evidence Based Updates…
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RT @WICSBottomLine: #TBL 462 SAHARA – Liberal vs Restrictive Transfusion Targets in SAH https://t.co/AbZBo5uqpr Article by English Review b…