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Mashup Score: 3Visual Function Measurements in Eyes with Diabetic Retinopathy: An Expert Opinion on Available Measures - 22 hour(s) ago
Visual function impairment from diabetic retinopathy can have a considerable impact on patient’s quality of life. Best-corrected visual acuity (BCVA) is most commonly used to assess visual function and guide clinical trials. However, BCVA is affected late in the disease process, is not affected in early disease, and does not capture some of the visual disturbances described by patients with diabetes.
Source: www.ophthalmologyscience.orgCategories: General Medicine News, OphthalmologyTweet
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Mashup Score: 24Genotype-phenotype correlations of ocular posterior segment abnormalities in Marfan syndrome - 5 day(s) ago
Marfan syndrome (MFS) is a connective tissue disorder caused by mutations in the FBN1 gene. In addition to typical phenotypes such as ectopia lentis and aortic dilation, MFS patients are prone to ocular posterior segment abnormalities, including retinal detachment, maculopathy, and posterior staphyloma. This study aims to investigate the correlations between FBN1 genotype and posterior segment abnormalities within a Chinese cohort of MFS.
Source: www.ophthalmologyscience.orgCategories: General Medicine News, OphthalmologyTweet
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Mashup Score: 14Current Issue Table of Contents: Ophthalmology Science - 5 day(s) ago
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Source: www.ophthalmologyscience.orgCategories: General Medicine News, OphthalmologyTweet
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Mashup Score: 2
We used exact matching and inverse propensity score weighting (IPSW) using real-world data (RWD) from the American Academy of Ophthalmology IRIS® Registry (Intelligent Research in Sight) to emulate the two pro re nata (prn) treatment arms from the Comparison of AMD Treatment Trial (CATT) and to compare the outcomes of the RWD arms to the two monthly treatment arms from the clinical trial.
Source: www.ophthalmologyscience.orgCategories: General Medicine News, OphthalmologyTweet
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Mashup Score: 5Development and Clinical Evaluation of a CRISPR/Cas12a-based Nucleic Acid Detection Platform for the Diagnosis of Keratomycoses - 11 day(s) ago
The objective of this study was to develop a rapid and accurate CRISPR/Cas12a-based molecular diagnostic assay (Rapid Identification of Mycoses using CRISPR, RID-MyC Assay) to detect fungal nucleic acids and to compare it with existing conventional mycologic methods for the diagnosis of fungal keratitis (FK).
Source: www.ophthalmologyscience.orgCategories: General Medicine News, OphthalmologyTweet
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Mashup Score: 2Rationale of Basic and Cellular Mechanisms Considered in Updating the Staging System for Diabetic Retinal Disease - 13 day(s) ago
To review preclinical and clinical evidence on basic and cellular mechanisms potentially pertinent to diabetic retinal disease (DRD) that might eventually be relevant to update the DRD staging system.
Source: www.ophthalmologyscience.orgCategories: General Medicine News, OphthalmologyTweet
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Mashup Score: 6
Physiological changes in retinal ganglion cells (RGCs) have been reported in rodent models of photoreceptor (PR) loss but this has not been investigated in primates. By expressing both a calcium indicator (GCaMP6s) and an optogenetic actuator (ChrimsonR) in foveal RGCs of the macaque, we reactivated RGCs in vivo and assessed their response in the weeks and years following PR loss.
Source: www.ophthalmologyscience.orgCategories: General Medicine News, OphthalmologyTweet
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Mashup Score: 39Automatic measurement and comparison of normal eyelid contour by age and gender using image-based deep learning - 20 day(s) ago
This study aimed to propose a fully automatic eyelid measurement system and compare the contours of both the upper and lower eyelids of normal individuals according to age and gender.
Source: www.ophthalmologyscience.orgCategories: General Medicine News, OphthalmologyTweet
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Mashup Score: 68High Dose Rate Yttrium (90Y) Episcleral Plaque Brachytherapy for Iris and Iridociliary Melanoma - 21 day(s) ago
To describe a pilot study on the use of single-session, high-dose-rate, FDA-cleared, yttrium-90 (90Y) plaque brachytherapy for iris and iridociliary melanoma.
Source: www.ophthalmologyscience.orgCategories: General Medicine News, OphthalmologyTweet
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Mashup Score: 8Familial exudative vitreoretinopathy with and without pathogenic variants of Norrin/β-catenin signaling genes - 21 day(s) ago
To determine the clinical characteristics of familial exudative vitreoretinopathy (FEVR) associated with or without pathogenic variants of the Norrin/β-catenin genes.
Source: www.ophthalmologyscience.orgCategories: General Medicine News, OphthalmologyTweet
Future prospective studies of patients with early and advanced retinopathy are needed to determine if current visual function tests can be used clinically or as endpoints for clinical trials. https://t.co/Ax0voV2h5J https://t.co/5VjRNJeTBA