Colorectal cancer is the third most common cancer in the United States, with colonoscopy being the preferred screening method. Up to 25% of colonoscopies are associated with poor preparation which leads to prolonged procedure time, repeat colonoscopies, and decreased adenoma detection. Artificial intelligence (AI) is being increasingly used in medicine, assessing medical school exam questions, and writing medical reports. Its use in gastroenterology has been used to educate patients with cirrhosis and hepatocellular carcinoma, answer patient questions about colonoscopy and provide correct colonoscopy screening intervals, having the ability to augment the patient–provider relationship.