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Mashup Score: 17Genomic Landscape of Lynch Syndrome Colorectal Neoplasia Identifies Shared Mutated Neoantigens for Immunoprevention - 2 day(s) ago
This study provides the combined mutational and transcriptomic landscape along with a catalog of immunologically validated neoantigens in Lynch syndrome colonic precancers and tumors that will facilitate cancer immunoprevention strategies.
Source: www.gastrojournal.orgCategories: General Medicine News, GastroenterologyTweet
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Mashup Score: 8Phases of Metabolic and Soft Tissue Changes in Months Preceding a Diagnosis of Pancreatic Ductal Adenocarcinoma - 5 day(s) ago
Identifying metabolic abnormalities that occur before pancreatic ductal adenocarcinoma (PDAC) diagnosis could increase chances for early detection. We collected data on changes in metabolic parameters (glucose, serum lipids, triglycerides; total, low-density, and high-density cholesterol; and total body weight) and soft tissues (abdominal subcutaneous fat [SAT], adipose tissue, visceral adipose tissue [VAT], and muscle) from patients 5 years before the received a diagnosis of PDAC.
Source: www.gastrojournal.orgCategories: General Medicine News, Hem/OncsTweet-
Prior study summary graphic below: Phases of Metabolic and Soft Tissue Changes in Months Preceding a Diagnosis of #PancreaticCancer https://t.co/EU1QycMkKl Body composition changes especially VAT/SAT changes and biochemical metabolic perturbations (serum lipids and glucose) can… https://t.co/25SA31UDGH https://t.co/ube18aKjx9
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Mashup Score: 11Oncogenic Fatty Acid Metabolism Rewires Energy Supply Chain in Gastric Carcinogenesis - 7 day(s) ago
Oncogenic gene activation in gastric proenzyme-secreting cells can lead to the carcinogenic process in gastric cancer development. Metabolic changes are essential for precancerous cell lineage progression into cancerous cells.
Source: www.gastrojournal.orgCategories: General Medicine News, GastroenterologyTweet
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Mashup Score: 17Cancer-Associated Fibroblast Induces Acinar-to-Ductal Cell Transdifferentiation and Pancreatic Cancer Initiation Via LAMA5/ITGA4 Axis - 9 day(s) ago
Pancreatic cancer inception and early detection remain elusive. Complex cellular crosstalk transforming normal cells toward tumor development by means of novel cell signaling mechanism has been identified as the potential culprit.
Source: www.gastrojournal.orgCategories: General Medicine News, GastroenterologyTweet
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Mashup Score: 7Thoracoabdominal Wall Motion–Guided Biofeedback Treatment of Abdominal Distension: A Randomized Placebo-Controlled Trial - 9 day(s) ago
A simple and effective biofeedback technique, guided by the motion of the abdominal and thoracic walls, is introduced to treat abdominal distension in patients with digestive disorders.
Source: www.gastrojournal.orgCategories: General Medicine News, GastroenterologyTweet
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Mashup Score: 17Histologic Remission in Inflammatory Bowel Disease and Female Fertility: A Nationwide Study - 11 day(s) ago
The findings of this nationwide study suggest that achieving histologic remission of inflammatory bowel disease may improve the chances of conceiving a child, even among women with clinically quiescent disease.
Source: www.gastrojournal.orgCategories: General Medicine News, GastroenterologyTweet
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Mashup Score: 23
A small advantage for early initiation of biologics was demonstrated in Crohn’s disease, but this was not the case in ulcerative colitis.
Source: www.gastrojournal.orgCategories: General Medicine News, GastroenterologyTweet
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Mashup Score: 23Current Issue Table of Contents: Gastroenterology - 16 day(s) ago
Login with your AGA username and password. Volume 165 Issue 2 p307-522,
Source: www.gastrojournal.orgCategories: General Medicine News, GastroenterologyTweet
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Mashup Score: 93Transcriptomic-Based Microenvironment Classification Reveals Precision Medicine Strategies for Pancreatic Ductal Adenocarcinoma - 17 day(s) ago
Transcriptomic-based tumor microenvironment classification identifies 4 prognostically distinct pancreatic ductal adenocarcinoma subtypes that can serve as a framework for patient selection to precision medicine trials.
Source: www.gastrojournal.orgCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 137Hepatorenal Syndrome in Cirrhosis - 21 day(s) ago
Hepatorenal syndrome (HRS) is a form of kidney dysfunction that characteristically occurs in liver cirrhosis. It is characterized by a marked impairment of kidney function in response to circulatory and hemodynamic alterations that occur in advanced stages of liver cirrhosis, aggravated by systemic inflammation and bacterial translocation. The classical definitions of the types of HRS have been recently revisited and 2 forms of HRS have been redefined: the acute form, referred to as acute kidney injury (HRS-AKI), and the chronic form, referred to as chronic kidney disease.
Source: www.gastrojournal.orgCategories: General Medicine News, GastroenterologyTweet
Study finds genomic landscape of lynch syndrome #colorectalneoplasia identifies shared mutated neoantigens for immunoprevention ➡️ https://t.co/hgU2SefUl5 https://t.co/Yt9n4v0Fo9