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Mashup Score: 18
Type 2 diabetes mellitus (T2DM) has reached pandemic levels, posing significant challenges to global public health systems. The World Health Organization (WHO) projects that over 9 % of the global adult population will be affected by 2030 [1]. The latest Global Burden of Disease (GBD) data indicate that in 2021, 529 million individuals worldwide were living with diabetes, with 96.0 % of these cases attributed to T2DM [2]. Among individuals aged 20–79, an estimated 485 million were diagnosed with diabetes.
Categories: General Medicine News, General HCPsTweet
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Mashup Score: 1
Many individuals with intermediate hyperglycaemia (IH), including impaired fasting glycaemia (IFG) and impaired glucose tolerance (IGT), as presently defined, will progress to type 2 diabetes (T2D). There is confirmatory evidence that T2D can be prevented by lifestyle modification and/or medications, in people with IGT diagnosed by 2-h plasma glucose (PG) during a 75-gram oral glucose tolerance test (OGTT). Over the last 40 years, a wealth of epidemiological data has confirmed the superior value of 1-h plasma glucose (PG) over fasting PG (FPG), glycated haemoglobin (HbA1c) and 2-h PG in populations of different ethnicity, sex and age in predicting diabetes and associated complications including death.
Categories: General Medicine News, Hem/OncsTweet-
International Diabetes Federation Position Statement on the 1-hour post-load plasma glucose for the diagnosis of intermediate hyperglycaemia and type 2 diabetes - Diabetes Research and Clinical Practice https://t.co/jWA63MYK8V
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Mashup Score: 62Diabetes as a risk factor for MASH progression - 2 month(s) ago
Non-alcoholic (now: metabolic) steatohepatitis (MASH) is the progressive inflammatory form of metabolic dysfunction-associated steatotic liver disease (MASLD), which often coexists and mutually interacts with type 2 diabetes (T2D), resulting in worse hepatic and cardiovascular outcomes. Understanding the intricate mechanisms of diabetes-related MASH progression is crucial for effective therapeutic strategies. This review delineates the multifaceted pathways involved in this interplay and explores potential therapeutic implications.
Categories: General Medicine News, CardiologistsTweet-
RT @scottisaacsmd: Risk factors for #MASH progression in people with type 2 #diabetes. https://t.co/x9hD7SIPRB https://t.co/fl4pXsdxZl
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Mashup Score: 62Diabetes as a risk factor for MASH progression - 2 month(s) ago
Non-alcoholic (now: metabolic) steatohepatitis (MASH) is the progressive inflammatory form of metabolic dysfunction-associated steatotic liver disease (MASLD), which often coexists and mutually interacts with type 2 diabetes (T2D), resulting in worse hepatic and cardiovascular outcomes. Understanding the intricate mechanisms of diabetes-related MASH progression is crucial for effective therapeutic strategies. This review delineates the multifaceted pathways involved in this interplay and explores potential therapeutic implications.
Categories: General Medicine News, CardiologistsTweet-
RT @scottisaacsmd: Risk factors for #MASH progression in people with type 2 #diabetes. https://t.co/x9hD7SIPRB https://t.co/fl4pXsdxZl
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Mashup Score: 62Diabetes as a risk factor for MASH progression - 2 month(s) ago
Non-alcoholic (now: metabolic) steatohepatitis (MASH) is the progressive inflammatory form of metabolic dysfunction-associated steatotic liver disease (MASLD), which often coexists and mutually interacts with type 2 diabetes (T2D), resulting in worse hepatic and cardiovascular outcomes. Understanding the intricate mechanisms of diabetes-related MASH progression is crucial for effective therapeutic strategies. This review delineates the multifaceted pathways involved in this interplay and explores potential therapeutic implications.
Categories: General Medicine News, CardiologistsTweet-
RT @scottisaacsmd: Risk factors for #MASH progression in people with type 2 #diabetes. https://t.co/x9hD7SIPRB https://t.co/fl4pXsdxZl
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Mashup Score: 60Diabetes as a risk factor for MASH progression - 3 month(s) ago
Non-alcoholic (now: metabolic) steatohepatitis (MASH) is the progressive inflammatory form of metabolic dysfunction-associated steatotic liver disease (MASLD), which often coexists and mutually interacts with type 2 diabetes (T2D), resulting in worse hepatic and cardiovascular outcomes. Understanding the intricate mechanisms of diabetes-related MASH progression is crucial for effective therapeutic strategies. This review delineates the multifaceted pathways involved in this interplay and explores potential therapeutic implications.
Categories: General Medicine News, CardiologistsTweet-
RT @scottisaacsmd: Risk factors for #MASH progression in people with type 2 #diabetes. https://t.co/x9hD7SIPRB https://t.co/fl4pXsdxZl
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Mashup Score: 4Global health impacts of high BMI: A 30-Year analysis of trends and disparities across regions and Demographics - 3 month(s) ago
The increasing prevalence of obesity has become a critical global health issue over the past few decades [1]. High body mass index (BMI), which is a key indicator of obesity, has seen a dramatic rise worldwide, leading to significant increases in related health problems, including cardiovascular diseases, type 2 diabetes, and various forms of cancer [2,3]. The role of high BMI as a major risk factor for both morbidity and mortality is well-established, affecting populations in both developed and developing regions [4,5].
Categories: General Medicine News, General HCPsTweet-
Global health impacts of high BMI: A 30-Year analysis of trends and disparities across regions and Demographics - Diabetes Research and Clinical Practice https://t.co/KyHKHMoLnP
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Mashup Score: 0Molecular mechanisms of gut microbiota in diabetic nephropathy - 7 month(s) ago
Diabetic nephropathy is a common complication of diabetes and a considerable contributor to end-stage renal disease. Evidence indicates that glucose dysregulation and lipid metabolism comprise a pivotal pathogenic mechanism in diabetic nephropathy. However, current treatment outcomes are limited, as they only provide symptomatic relief without preventing disease progression. The gut microbiota is a group of microorganisms that inhabit the human intestinal tract and play a crucial role in maintaining host energy balance, metabolism, and immune activity.
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Molecular mechanisms of gut microbiota in diabetic nephropathy - Diabetes Research and Clinical Practice https://t.co/eXusxCHcdq
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Mashup Score: 5
Social networking services (SNS) can facilitate real-time communication and feedback of blood glucose and other physiological data between patients and healthcare professionals. This systematic review and meta-analysis aims to summarise the current evidence surrounding the role of online social networking services in diabetes care.
Categories: General Medicine News, CardiologistsTweet-
「SNSがDMコントロールを改善させる」という研究が2014にすでにあったと知る． 専門外学会参加すると新たな発見は多い． Online social networking services in the management of patients with diabetes mellitus: Diabetes Research and Clinical Practice https://t.co/hKNPaq7boQ
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Mashup Score: 59Type 2 diabetes mellitus and cardiometabolic outcomes in metabolic dysfunction-associated steatotic liver disease population - 8 month(s) ago
The metabolic syndrome is a constellation of epidemics, involving type 2 diabetes mellitus (T2DM), hypertension, hyperlipidemia, and obesity, that share common biological and societal pathways.[1–4] This pathological metabolic milieu collectively increases the individual’s risk of cardiovascular diseases, including coronary heart disease and heart failure.[3,5,6] More recently, metabolic dysfunction-associated steatotic liver disease (MASLD) has been increasingly recognized as a key manifestation of this systemic metabolic disease.
Categories: General Medicine News, CardiologistsTweet-
RT @scottisaacsmd: Cardiovascular disease is the leading cause of mortality in #MASLD and type 2 diabetes. https://t.co/f0CPOtrv4x https://…
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Global, regional, and national burden of type 2 diabetes mellitus attributable to particulate matter pollution from 1990 to 2021: An analysis of the global burden of disease study 2021 - Diabetes Research and Clinical Practice https://t.co/9enGno7d66