A 25-month-old boy presented with upward and inward deviation of the left eye, noticed since infancy, and progressive swelling of the left lower eyelid (A). Examination showed left eye blindness, microcornea, and a palpable orbital mass, whereas the right eye was normal. Magnetic resonance imaging revealed a microphthalmic globe with large posterior orbital cysts and significant left orbital expansion (B). The cyst was hypointense on T1-weighted and hyperintense on T2-weighted imaging. After informed consent, enucleation and cyst excision were performed, revealing optic nerve compression (C).

A 53-year-old man presented with debilitating glare only in the right eye 1 year after an airbag-deployed unrestrained motor vehicle accident. Six years previously, he had uncomplicated right eye cataract surgery with diffractive multifocal intraocular lens (IOL) implantation. On examination, uncorrected visual acuity was 20/25, with normal intraocular pressure and corneal topography. Examination of the right eye revealed diffuse iris transillumination defects with micro-sphincter tears (A and B) with a well-centered multifocal IOL, and an unaffected left eye.

A 19-year-old man presented with a 10-year history of progressively enlarging bilateral conjunctival lesions. Anterior-segment examination (A, B) revealed 360-degree bilateral involvement of the bulbar conjunctiva, extending from the fornix to the limbus, with the palpebral conjunctiva remaining unremarkable. Occasional hemorrhages were observed. Anterior-segment OCT exhibited hyperreflective subepithelial lesions containing hyperreflective foci bilaterally (C, red arrows), with a normal overlying epithelial layer.