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Mashup Score: 4Rural exclusion from science and academia - 3 year(s) ago
Rural individuals are underrepresented in science at all levels. The disenfranchisement of rural people in science and research foments a cultural divide between rural America and the scientific community. Science can improve inclusion of rural individuals by removing barriers in academia that disfavor those from first-generation and low-socioeconomic backgrounds.
Source: Trends in MicrobiologyCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 0
Despite the recent increase in knowledge concerning microorganisms, the processes determining their global distribution and functioning have not been disentangled. Microbial dormant stages are adapted to endure specific adverse conditions related to their dispersion path, suggesting that dispersion is not entirely a stochastic process. Long-term dormancy enhances microbial dispersion, promoting…
Source: Trends in MicrobiologyCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 2
Motility allows many microbes to traverse their environment to find nutrient sources or escape unfavorable environments. However, some microbes are nonmotile and are restricted to their immediate conditions. Intriguingly, sporadic reports have demonstrated that many nonmotile microbes can utilize the motility machinery of other microbes in their vicinity. This form of transportation, called…
Source: Trends in MicrobiologyCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 8Molecular Determinants of SARS-CoV-2 Variants - 3 year(s) ago
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) evolution is expected, given the nature of virus replication. Selection and establishment of variants in the human population depend on viral fitness and on molecular and immunological selection pressures. Here we discuss how mechanisms of replication and recombination may contribute to the emergence of current and future variants of…
Source: Trends in MicrobiologyCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 16Molecular Determinants of SARS-CoV-2 Variants - 3 year(s) ago
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) evolution is expected, given the nature of virus replication. Selection and establishment of variants in the human population depend on viral fitness and on molecular and immunological selection pressures. Here we discuss how mechanisms of replication and recombination may contribute to the emergence of current and future variants of…
Source: Trends in MicrobiologyCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 4
In certain niches, microbes encounter environmental challenges that are temporally linked. In such cases, microbial fitness is enhanced by the evolution of anticipatory responses where the initial challenge simultaneously activates pre-emptive protection against the second impending challenge. The accumulation of anticipatory responses in domesticated yeasts, which have been termed ‘adaptive…
Source: Trends in MicrobiologyCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 2
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections present with increased disease severity and poor clinical outcomes in diabetic patients compared with their nondiabetic counterparts. Diabetes/hyperglycemia-triggered endothelial dysfunction and hyperactive inflammatory and immune responses are correlated to twofold to threefold higher intensive care hospitalizations and more…
Source: Trends in MicrobiologyCategories: Cardiologists, Latest HeadlinesTweet-
This is an interesting article published in @CellCellPress @TrendsCellBio Therapeutic Potential of #Metformin in COVID-19: Reasoning for Its Protective Role https://t.co/2qU8LnYBQX @DrJennHaythe @JGrapsa @ErinMichos @EricTopol @JJheart_doc @AnastasiaSMihai @pabeda1 @JJheart_doc https://t.co/PAwnXCPaYK
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Mashup Score: 6Flexibility and Adaptability of Quorum Sensing in Nature - 3 year(s) ago
Quorum sensing (QS), a type of chemical communication, allows bacteria to sense and coordinate activities in natural biofilm communities using N-acyl homoserine lactones (AHLs) as one type of signaling molecule. For AHL-based communication to occur, bacteria must produce and recognize the same signals, which activate similar genes in different species. Our current understanding of AHL-QS suggests…
Source: Trends in MicrobiologyCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 6A Radical Reimagining of Fungal Two-Component Regulatory Systems - 3 year(s) ago
Bacterial two-component regulatory systems (TCSs) mediate signal transduction by transferring phosphoryl groups between sensor kinase and response regulator proteins, sometimes using intermediary histidine-phosphotransferase (Hpt) domains to form multistep phosphorelays. Because (i) almost all known fungal sensor kinases exhibit a domain architecture characteristic of bacterial TCS phosphorelays,…
Source: Trends in MicrobiologyCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 3
Pandemics are caused by novel pathogens to which pre-existing antibody immunity is lacking. Under these circumstances, the body must rely on innate interferon-mediated defenses to limit pathogen replication and allow development of critical humoral protection. Here, we highlight studies on disease susceptibility during H1N1 influenza and COVID-19 (SARS-CoV-2) pandemics. An emerging concept is…
Source: Trends in MicrobiologyCategories: General Medicine News, Latest HeadlinesTweet
Rural exclusion from science and academia #TrendsVoices @TrendsMicrobiol @DrLindzyONeal https://t.co/FRHm45Dq3m https://t.co/4Dtz2il34N