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Mashup Score: 1Endpoints and Outcomes After Immunotherapy for Food Allergy: What Is Meaningful for Patients? - 1 year(s) ago
Multiple novel interventions for food allergy are currently at various stages of development with the goal of reducing or eliminating allergic reactions. However, the relative success of these therapeutics in achieving meaningful, long-term improvements to patients’ lives is difficult to determine as there is currently very limited understanding of the degree of alignment between clinical trial…
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Mashup Score: 1
Oral food challenges (OFCs) are currently the definitive diagnostic procedure in food allergy. Their design has evolved over the decades to maximize safety, optimize convenience, and address several specific clinical questions. However, they are a resource-intensive investigation that carry a risk for severe allergic reaction in which fatal outcomes, although rare, have been reported. In this…
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Mashup Score: 0Precautionary Allergen Labeling: What Advice Is Available for Health Care Professionals, Allergists, and Allergic Consumers? - 1 year(s) ago
In most countries, the use of precautionary allergen labeling (PAL) is not governed by regulation. PAL was initially identified as a judicious risk management measure to address instances of “unavoidable” cross-contact with priority food allergens during food processing. However, PAL has gradually been devalued in part due to overuse and inconsistent application by the food industry. Currently,…
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Mashup Score: 0
There are hypersensitivity reactions (HRs) to foods in which nonsteroidal anti-inflammatory drugs (NSAIDs) act as aggravating factors (NSAID-exacerbated food allergy, NEFA) or cofactors (NSAID-induced food allergy, NIFA), often misdiagnosed as HRs to NSAIDs. Urticarial/angioedematous and/or anaphylactic reactions to ≥ 2 chemically unrelated NSAIDs do not meet the current classification criteria….
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Mashup Score: 0Identification of Motivators and Barriers Impacting Successful Food Introduction or Reintroduction after Negative Oral Food Challenges - 1 year(s) ago
Article infoPublication historyAccepted: March 14, 2023Received in revised form: January 20, 2023Received: February 14, 2022Publication stageIn Press Journal Pre-ProofFootnotesConflict of InterestDisclosure of potential conflict of interest: C.M.D., R.H.H., S.W., C.H.L., M.A.F., S.O.Z., J.A.H., L.H. A.R.A., M.A., D.H. declare…
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Mashup Score: 1sCD14 and intestinal fatty acid binding protein are elevated in the serum of patients with idiopathic anaphylaxis. - 1 year(s) ago
Intestinal epithelial integrity compromise has been identified in gastrointestinal (GI), atopic, and autoimmune diseases.
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Mashup Score: 1Food-dependent exercise-induced wheals/angioedema, anaphylaxis, or both: A systematic review of phenotypes - 1 year(s) ago
Food-dependent exercise-induced allergic reactions can manifest with wheals, angioedema, and anaphylaxis, alone or in combination.
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Mashup Score: 5A systematic review of patient-reported adherence measures in asthma: Which questionnaire is most useful in clinical practice? - 1 year(s) ago
Suboptimal adherence to inhaled corticosteroid (ICS) in asthma is a worryingly prevalent yet modifiable factor in uncontrolled disease. Several objective measures of adherence exist, but they are time consuming. The use of patient-reported adherence measures (PRAMs) could therefore offer a time-efficient pragmatic approach to adherence assessment in clinical practice and potentially the…
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Mashup Score: 0A Comparison of Topical Corticosteroids and Topical Calcineurin Inhibitors for the Treatment of Atopic Dermatitis - 1 year(s) ago
Topical corticosteroids (TCS) are a mainstay of treatment for atopic dermatitis (AD). There are shared physician and patient concerns that TCS use can result in skin atrophy and systemic absorption. The clinical use of topical calcineurin inhibitors (TCI) for AD is relatively limited despite evidence that TCI are safe and effective. Understanding the differences in efficacy and adverse effects…
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Mashup Score: 0Cytokine Storm Syndromes in Pediatric Patients - 1 year(s) ago
Cytokine storm syndromes (CSS) represent a diverse group of disorders characterized by severe overactivation of the immune system. In the majority of patients, CSS arise from a combination of host factors, including genetic risk and predisposing conditions, and acute triggers such as infections. CSS present differently in adults then in children, who are more likely to present with monogenic…
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