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Mashup Score: 0Engineered Salmonella inhibits GPX4 expression and induces ferroptosis to suppress glioma growth in vitro and in vivo - Journal of Neuro-Oncology - 10 month(s) ago
Purpose Glioma is a life-threatening malignancy where conventional therapies are ineffective. Bacterial cancer therapy has shown potential for glioma treatment, in particular, the facultative anaerobe Salmonella has been extensively studied. Meanwhile, ferroptosis is a newly characterized form of cell death. Nevertheless, the role of ferroptosis in Salmonella-induced tumour cell death remains…
Source: SpringerLinkCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 0Healthcare utilization and unmet needs of patients with antisynthetase syndrome: An international patient survey - Rheumatology International - 10 month(s) ago
Antisynthease syndrome (ASSD) is a rare, complex and understudied autoimmune disease. Internet-based studies can overcome barriers of traditional on-site research and are therefore very appealing for rare diseases. The aim of this study was to investigate patient-reported symptoms, diagnostic delay, symptoms, medical care, health status, working status, disease knowledge and willingness to…
Source: SpringerLinkCategories: Latest Headlines, RheumatologyTweet-
Healthcare utilization & unmet needs of patients with antisynthetase syndrome: international patient survey. Diagnostic delay 1 yr. 67.4% fatigue, 55.1% myalgia at disease onset. Myositis, joint, lung disease 17.8% at onset & 37.3% during disease course https://t.co/SVqEr6omvJ
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Mashup Score: 0Creating Value Through “Accompaniment” in Primary Care: a Call for Advocacy - Journal of General Internal Medicine - 10 month(s) ago
Journal of General Internal Medicine –
Source: SpringerLinkCategories: Healthcare Professionals, Latest HeadlinesTweet-
'Creating value through accompaniment in primary care' via @russphillips53 https://t.co/18Qofr6dMi @sib313 @HelenRSalisbury @pwhitakerwriter https://t.co/kNTOEyMyDc https://t.co/h176g4i9SG
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Mashup Score: 9Does Regular Physical Activity Mitigate the Age-Associated Decline in Pulmonary Function? - Sports Medicine - 10 month(s) ago
Whereas the negative effects of aging and smoking on pulmonary function are undisputed, the potential favorable effects of physical activity on the aging process of the otherwise healthy lung remain controversial. This question is of particular clinical relevance when reduced pulmonary function compromises aerobic exercise capacity (maximal oxygen consumption) and thus contributes to an increased…
Source: SpringerLinkCategories: Latest Headlines, RheumatologyTweet-
RT @agingdoc1: Does Regular Physical Activity Mitigate the Age-Associated Decline in Pulmonary Function? https://t.co/B2Bz0FewX8 @SportsM…
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Mashup Score: 0Evaluation of Coronary Microvascular and Endothelial Function in the Cardiac Catheterization Laboratory - Current Treatment Options in Cardiovascular Medicine - 10 month(s) ago
Purpose of review Coronary endothelial and microvascular dysfunction leads to chronic angina (ANOCA) and ischemia (INOCA) in the absence of obstructive epicardial coronary artery disease. These highly prevalent conditions have been associated with increased morbidity and mortality. Comprehensive coronary reactivity testing (CRT) is performed in the cardiac catheterization laboratory to definite…
Source: SpringerLinkCategories: Cardiologists, Latest HeadlinesTweet-
2 new 🔥 off the press papers 1️⃣ How to perform coronary endo and micro fx assessment in cath lab @MuhammadAjmalMD @DrArgyle 👇 https://t.co/Mg2sViGdrI 2️⃣ Assessment of coronary micro & endo function ⬇️ downstream healthcare cost by ~25k/pt in 2 yrs! https://t.co/hjujOxxH0a https://t.co/q1mDhwvtOR
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Mashup Score: 1Radiologically supervised bowel management program outcome in patients with chronic idiopathic constipation - Pediatric Surgery International - 10 month(s) ago
Purpose This study aimed to analyze our radiologically supervised bowel management program (RS-BMP) outcomes in patients with chronic idiopathic constipation (CIC). Methods A retrospective study was conducted. We included all patients with CIC who participated in our RS-BMP at Children´s Hospital Colorado from July 2016 to October 2022. Results Eighty patients were included. The average time with…
Source: SpringerLinkCategories: Healthcare Professionals, Latest HeadlinesTweet-
Radiologically supervised bowel management program outcome in patients with chronic idiopathic constipation #some4pedsurg #some4surgery #SpringerLink https://t.co/pCbzuWqoG5
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Mashup Score: 2Radiologically supervised bowel management program outcome in patients with chronic idiopathic constipation - Pediatric Surgery International - 10 month(s) ago
Purpose This study aimed to analyze our radiologically supervised bowel management program (RS-BMP) outcomes in patients with chronic idiopathic constipation (CIC). Methods A retrospective study was conducted. We included all patients with CIC who participated in our RS-BMP at Children´s Hospital Colorado from July 2016 to October 2022. Results Eighty patients were included. The average time with…
Source: SpringerLinkCategories: Healthcare Professionals, Latest HeadlinesTweet-
Radiologically supervised bowel management program outcome in patients with chronic idiopathic constipation #some4surgery #some4pedsurg #sminaev #constipation #SpringerLink https://t.co/pCbzuWqoG5
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Mashup Score: 0Revisiting the Time Needed to Provide Adult Primary Care - Journal of General Internal Medicine - 10 month(s) ago
Background Many patients do not receive guideline-recommended preventive, chronic disease, and acute care. One potential explanation is insufficient time for primary care providers (PCPs) to provide care. Objective To quantify the time needed to provide 2020 preventive care, chronic disease care, and acute care for a nationally representative adult patient panel by a PCP alone, and by a PCP as…
Source: SpringerLinkCategories: Hem/Oncs, Latest HeadlinesTweet-
Primary care docs like me squeeze 26.7 hours (!) of work into a day (https://t.co/wXXtiT116t). The party line to docs for so long has been: we don't know how, but just squeeze more in. Patients deserve better access. But it can't come by telling docs "just one more thing."
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Mashup Score: 0Factors Affecting Success of New Drug Clinical Trials - Therapeutic Innovation & Regulatory Science - 10 month(s) ago
Clinical trials are an essential process in the development of new drugs. In spite of time-consuming processes and high costs, the overall success rate of clinical trials is only 7.9%, which is a high risk for biopharmaceutical companies. However, despite these huge risks, research on finding factors affecting clinical trials to overcome and manage to risks has been insufficient. Considering…
Source: SpringerLinkCategories: Hem/Oncs, Latest HeadlinesTweet-
I suspect a lot of these are colliders rather than causal. Factors Affecting Success of New Drug Clinical Trials | @springerlink https://t.co/PxAomTAcuy
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Mashup Score: 3Non-coding RNA in cardiovascular diseases: mechanisms, biomarkers, and therapeutic targets - 10 month(s) ago
Cardiovascular disease is still the leading cause of death globally. Non-coding RNAs (ncRNAs) such as microRNAs (miRNAs), long non-coding RNAs (lncRNAs), and …
Source: SpringerLinkCategories: Cardiologists, Latest HeadlinesTweet-
RT @BenedettaIzzi: Working on #NonCodingRNA in #CVD? we're calling for great stories to be published in #JCTR👉https://t.co/55kxT5XqdK #ISCT…
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New strategy to increase the effect of bacteria in glioma therapy? In a recent article by Chen et al., Salmonella was found to induce ferroptosis, a newly characterized type of cell death, thereby suppressing glioma growth. Read more here: https://t.co/fQRYYrRTyd https://t.co/I6Y817xz7C