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Mashup Score: 0Sleep behaviour differs in women and men with psoriatic arthritis and axial spondyloarthritis with impact on quality of life and depressive symptoms - 12 month(s) ago
Objectives Axial spondyloarthritis (axSpA) and psoriatic arthritis (PsA) may have a profound impact on sleep and health-related quality of life. The aim of this study was to assess sleep quality and quality of life and determine associated factors in patients treated with spondyloarthritides (SpA). Methods Cross-sectional questionnaire-based assessment of sleep behaviour, quality of life,…
Source: RMD OpenCategories: Latest Headlines, RheumatologyTweet
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Mashup Score: 0Methotrexate treatment in early psoriatic arthritis in comparison to rheumatoid arthritis: an observational nationwide study - 12 month(s) ago
Introduction We aimed to compare the proportions of patients with newly diagnosed psoriatic arthritis (PsA) and rheumatoid arthritis (RA) remaining on methotrexate (regardless of other disease-modifying antirheumatic drug (DMARD)-changes), and proportions not having started another DMARD (regardless of methotrexate discontinuation), within 2 years of starting methotrexate, as well as methotrexate…
Source: RMD OpenCategories: Healthcare Professionals, Latest HeadlinesTweet-
Swedish registry review of #MTX initiation in early #PsA vs #RA (n 3642each). 2 years after MTX start, 71% of PsA vs 76% of patients with RA remained on MTX & the majority (66%/60%) had not started another DMARD, or a biologic (77%/74%) https://t.co/nTJO04sn65 https://t.co/gLjKzj2c74
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Mashup Score: 7
A 68-year-old woman presented with bilateral swelling of the salivary glands, sicca symptoms of eyes and mouth, itching, fatigue and weight gain of about 5 kg in the last 2–3 years. As part of a careful diagnostic work up including lab tests for antinuclear antibodies (ANA), antibodies to extractable nuclear antigens (ENA), anti-neutrophilic cytoplasmatic antiobodies (ANCA), immunoglobulin…
Source: RMD OpenCategories: Latest Headlines, RheumatologyTweet-
A mimicker of #Sjogrens ➡️Kimura's disease ▶️salivary glands swelling ▶️allergic symptoms such as itching ▶️elevated levels of IgE ▶️ANA, anti-ENA, ANCA negative ▶️normal IgG4 levels Read the full text case report 👉 https://t.co/JmSWqcLEgh https://t.co/D6RzzzgCja
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Mashup Score: 0
Objectives To investigate whether repair of erosions and joint space narrowing (JSN) in rheumatoid arthritis (RA) occurs and whether clinical variables predict this. Methods Eight-year follow-up data of the BeSt-study were used. Patients with recent onset RA (1987 criteria) were randomised to four treatment strategies and treated-to-target (Disease Activity Score (DAS)≤2.4). Yearly radiographs…
Source: RMD OpenCategories: Latest Headlines, RheumatologyTweet-
New analyses of follow-up data from the BeSt-study: Initially randomized to four treatment strategies and treated-to-target After 8 years of #T2T 17/320 #RA patients (5.3%) showed signs of repair 10 --> regression of JSN 7 --> erosions https://t.co/FdFJhb1Sgz
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Mashup Score: 0
Objective To investigate sustained remission following the discontinuation of tofacitinib in patients with rheumatoid arthritis. Methods Patients who had an inadequate response to methotrexate (MTX) with or without biological disease-modifying antirheumatic drugs were randomly divided into two groups at baseline, and tofacitinib treatment in combination with MTX was administered to both groups….
Source: RMD OpenCategories: Latest Headlines, RheumatologyTweet-
open-label randomised study in #RA patients and inadequate #MTX response receiving #tofacitinib addon -48/113 in remission at week 52 then stop either tofa or MTX At week 104: 7/24 with tofa stop remain remission 10/20 with MTX stop remain in remission https://t.co/AgI6oUyWnn https://t.co/qAITxuB6T2
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Mashup Score: 0Fetal and maternal morbidity in pregnant patients with Lupus: a 10-year US nationwide analysis - 1 year(s) ago
Objective To evaluate and quantify the indicators of fetal and maternal morbidity in deliveries for patients with systemic lupus erythematosus (SLE) compared with deliveries in patients without SLE. Methods We used retrospective data from the National Inpatient Sample (NIS) to identify all delivery related hospital admissions of patients with and without SLE from 2008 to 2017 using ICD-9/10…
Source: RMD OpenCategories: General Medicine Journals and Societies, Latest HeadlinesTweet-
Mums with SLE at double the risk of having premature or growth restricted babies finds @ARD_BMJ research https://t.co/z3k8eU1kDE
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Mashup Score: 2
Objective To examine the performance of the new 2022 American College of Rheumatology (ACR)/EULAR giant cell arteritis (GCA) classification criteria for diagnosis in routine clinical care. Methods Multicentric retrospective observational study of patients referred to two ultrasound (US) fast track clinics. Patients with GCA were compared with unselected controls with suspected GCA. The gold…
Source: RMD OpenCategories: Latest Headlines, RheumatologyTweet-
How do the @ACRheum @eular_org classification criteria for #GCA perform in clinical practice: Multicentric retrospective observational study patients referred to two ultrasound (US) + Sensitivity 92.6% | specificity 71.8%, using GCA clinical diagnosis https://t.co/qif0v9aJWn
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Mashup Score: 5'Difficult to treat' rheumatoid arthritis: current position and considerations for next steps - 1 year(s) ago
The European Alliance of Associations for Rheumatology recently defined difficult to treat (D2T) rheumatoid arthritis (RA) and provided points to consider in its management. This review summarises the key concepts of D2T-RA that underpinned this recent guidance. D2T-RA is primarily characterised by failure of at least two different mechanism of action biologic/targeted synthetic disease-modifying…
Source: RMD OpenCategories: Latest Headlines, RheumatologyTweet-
Difficult-to-treat #Rheumatoid arthritis Evaluate ➡️ Presence or absence of inflammation ➡️Mimics +/- coexisting pathology ➡️Comorbidities ➡️Non adherence 👉🏼https://t.co/RHFZ1QueVx Via @ARD_BMJ via Prof Maya Buch #BSR23 https://t.co/mCWAIzDCi2
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Mashup Score: 0'Difficult to treat' rheumatoid arthritis: current position and considerations for next steps - 1 year(s) ago
The European Alliance of Associations for Rheumatology recently defined difficult to treat (D2T) rheumatoid arthritis (RA) and provided points to consider in its management. This review summarises the key concepts of D2T-RA that underpinned this recent guidance. D2T-RA is primarily characterised by failure of at least two different mechanism of action biologic/targeted synthetic disease-modifying…
Source: RMD OpenCategories: Latest Headlines, RheumatologyTweet-
Difficult-to-treat #Rheumatoid arthritis Evaluate ➡️ Presence or absence of inflammation ➡️Mimics +/- coexisting pathology ➡️Comorbidities ➡️Non adherence 👉🏼https://t.co/RHFZ1QueVx Via @ARD_BMJ via Prof Maya Buch #BSR23 https://t.co/ipgK0PAG4i
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Mashup Score: 0
Background Evaluate the impact of sex on tofacitinib efficacy, safety and persistence (time to discontinuation) in patients with psoriatic arthritis (PsA). Methods Data were pooled from two phase 3 randomised controlled trials. Patients were randomised to tofacitinib 5 mg or 10 mg two times per day, adalimumab 40 mg every 2 weeks or placebo. Efficacy outcomes to month 12 included American…
Source: RMD OpenCategories: Healthcare Professionals, Latest HeadlinesTweet-
Pooled data from 3 RCTs in PsA compared tofacitinib vs. adalimumab in 816 pts. Baseline, women had higher TJC, enthesitis, HAQ-DI, FACIT-F (Males more dactylitis). Sexes had equal ACR20/50/70, PASI75, ∆HAQ-DI, & persistence, but females less achieved MDA https://t.co/LICWVjI2kH https://t.co/8RipVIEWyJ
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❗️Patients with SpA continue to experience abnormal sleep behaviour despite treatment. 🚫😴associated with: 😔depression 🤸♀️functional capacity 🚺female sex 🦴axial involvement #openaccess https://t.co/S7h4f4yrqX