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Mashup Score: 8
Background: Chronic kidney disease (CKD) is a significant complication in patients with sickle cell disease (SCD), leading to increased mortality. Objective: This study aims to investigate the burden of CKD in Medicaid-enrolled adults with SCD in California, examine differences in disease burden between male and female individuals, and assess mortality rates and access to specialized care. Methods: This retrospective cohort study used the California Sickle Cell Data Collection program to identify and monitor individuals with SCD. Medicaid claims, vital records, emergency department, and hospitalization data from 2011 to 2020 were analyzed. CKD prevalence was assessed based on ICD (International Classification of Diseases) codes, and mortality rates were calculated. Access to specialized care was examined through outpatient encounter rates with hematologists and nephrologists. Results: Among the 2345 adults with SCD, 24.4% (n=572) met the case definition for CKD. The SCD-CKD group was o
Source: publichealth.jmir.orgCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 1
Background: The relationship between 24-hour rest-activity rhythms (RARs) and risk for dementia or mild cognitive impairment (MCI) remains an area of growing interest. Previous studies were often limited by small sample sizes, short follow-ups, and older participants. More studies are required to fully explore the link between disrupted RARs and dementia or MCI in middle-aged and older adults. Objective: We leveraged the UK Biobank data to examine how RAR disturbances correlate with the risk of developing dementia and MCI in middle-aged and older adults. Methods: We analyzed the data of 91,517 UK Biobank participants aged between 43 and 79 years. Wrist actigraphy recordings were used to derive nonparametric RAR metrics, including the activity level of the most active 10-hour period (M10) and its midpoint, the activity level of the least active 5-hour period (L5) and its midpoint, relative amplitude (RA) of the 24-hour cycle [RA=(M10-L5)/(M10+L5)], interdaily stability, and intradaily v
Source: publichealth.jmir.orgCategories: General Medicine News, Hem/OncsTweet-
Asso' of Rest-Activity Rhythm & Risk of Developing Dementia or MCI in Middle-Aged & Older Popltn: Prospective Cohort Study https://t.co/alJs5jHO7e via @AgustinMIbanez et al @ProfRobHoward @seb_walsh @ajlees @MadhavThambiset @LonSchneiderMD @EWidera @nvillain_alz @AlbertoEspay https://t.co/k0TsMogrdr
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Our study of #Medicaid enrollees with #sicklecelldisease in CA shows: - High prevalence of #CKD and mortality - 62% have not seen a #nephrologist - Access to care needs to improve Great collaboration @ucsdnephrology @HemUcsd @ChildrensAL https://t.co/FFV1LBeVTn