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Mashup Score: 6Aerosolized, Gas-Phase, Intravitreal Methotrexate Reduces Proliferative Vitreoretinopathy in a Randomized Trial in a Porcine Model - 1 year(s) ago
To determine the effectiveness of aerosol delivered methotrexate (AD-MTx) in a large-animal (porcine) model of proliferative vitreoretinopathy (PVR).
Source: Ophthalmology ScienceCategories: Latest Headlines, OphthalmologyTweet
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Mashup Score: 0Age Associations with Dry Eye Clinical Signs and Symptoms in the Dry Eye Assessment and Management (DREAM) Study - 1 year(s) ago
To evaluate how increasing age is associated with dry eye disease (DED) signs and symptoms in the Dry Eye Assessment and Management (DREAM) study. This study was undertaken to better understand how DED signs and symptoms differ across decades of life with goals to help assess detection and treatment of DED.
Source: Ophthalmology ScienceCategories: Latest Headlines, OphthalmologyTweet-
Secondary analysis of the DREAM study reveals #dryeye signs--but not symptoms--were significantly more severe with increasing age in women--but not men: https://t.co/5nX5jufnT4 @ScheieEye #ophthalmology
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Mashup Score: 3SynthEye: Investigating the impact of synthetic data on AI-assisted gene diagnosis of Inherited Retinal Disease - 1 year(s) ago
Rare disease diagnosis is challenging in medical image-based artificial intelligence due to a natural class imbalance in datasets, leading to biased prediction models. Inherited retinal diseases (IRDs) are a research domain that particularly faces this issue. This study investigates the applicability of synthetic data in improving AI-enabled diagnosis of IRDs using Generative Adversarial Networks…
Source: Ophthalmology ScienceCategories: Latest Headlines, OphthalmologyTweet-
New study investigates the impact of synthetic data augmentation using generative adversarial networks in #deeplearning-enabled diagnosis of inherited retinal diseases from fundus autofluorescence images. https://t.co/gJaK7NyLhT https://t.co/ED6c0nAgi4
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Mashup Score: 0Radiomics-Based Assessment of OCT Angiography Images for Diabetic Retinopathy Diagnosis - 1 year(s) ago
To evaluate the diagnostic accuracy of machine learning (ML) techniques applied to radiomic features extracted from OCT and OCT angiography (OCTA) images for diabetes mellitus (DM), diabetic retinopathy (DR), and referable DR (R-DR) diagnosis.
Source: Ophthalmology ScienceCategories: Latest Headlines, OphthalmologyTweet-
Study demonstrates that radiomic features extracted from OCTA images permit the identification of #diabeticretinopathy patients with #machinelearning classifiers & provides recommendations about specific scanning protocols for best model performances. https://t.co/ayE1YET5dE https://t.co/1Ijk6GjBPa
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Mashup Score: 6The Biological Character of Donor Corneal Endothelial Cells Influences Endothelial Cell Density Post Successful Corneal Transplantation - 1 year(s) ago
Corneal endothelial cell density (ECD) gradually decreases after corneal transplantation by unknown biological, biophysical or immunological mechanism. To assess the association between donor corneal endothelial cell (CEC) maturity in culture and postoperative endothelial cell loss (ECL) after successful corneal transplantation.
Source: Ophthalmology ScienceCategories: Latest Headlines, OphthalmologyTweet-
Prospective evidence that high maturity donor corneal endothelial cell content may predict long-term graft survival: https://t.co/nDxMLPKx3r #ophthalmology #cornea #transplant https://t.co/U8n5aImwk4
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Mashup Score: 0
To develop a method for objective analysis of the reproducible steps in routine cataract surgery.
Source: Ophthalmology ScienceCategories: Latest Headlines, OphthalmologyTweet-
Use of machine learning to assess cataract surgery skill level with tool detection in an ophthalmology residency program: https://t.co/4KyrZKivUU #ophthalmology #cataractsurgery https://t.co/qBnC3iT3bH
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Mashup Score: 7Loss of Corneal Nerves and Corneal Haze in Fuchs’ Endothelial Corneal Dystrophy Patients with the TCF4 Trinucleotide Repeat Expansion - 2 year(s) ago
Loss of corneal sub-basal nerve plexus and corneal haze correlate to disease severity of Fuchs’ endothelial corneal dystrophy in patients with the trinucleotide repeat expansion in the transcription factor 4 (TCF4) gene.
Source: Ophthalmology ScienceCategories: Latest Headlines, OphthalmologyTweet-
Corneal sub-basal nerve plexus loss & #cornea haze correlate w #FuchsDystrophy severity in pts w transcription factor 4 (TCF4) gene trinucleotide repeat expansion. Authors conclude this Fuchs subtype can be classified as neurodegenerative https://t.co/VuaoAlld96 #ophthalmology https://t.co/tAIpKJxzpu
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Mashup Score: 26Vitrectomy in diabetic macular edema - A swept-source optical coherence tomography (OCT) angiography study - 2 year(s) ago
The foveal avascular zone (FAZ) has been reported to decrease after anti-VEGF injections in diabetic macular edema (DME) in the long term. This study aimed to present the changes in Swept-Source OCT Angiography (SS-OCTA) after vitrectomy in patients with DME.
Source: Ophthalmology ScienceCategories: Latest Headlines, OphthalmologyTweet-
Vitrectomy in diabetic macular edema - a swept-source OCT angiography study https://t.co/JBKDZA8n36 https://t.co/FnUfcB2GGk
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Mashup Score: 19Identifying Novel Genes and Variants in Immune and Coagulation Pathways Associated with Macular Degeneration - 2 year(s) ago
To select individuals and families with low genetic burden for age-related macular degeneration (AMD), to inform the clinical diagnosis of macular disorders, and to find novel genetic variants associated with macular disease in affected families.
Source: Ophthalmology ScienceCategories: Latest Headlines, OphthalmologyTweet-
Study on genetic association analysis of #maculardegeneration suggests novel rare variants associated with maculopathy. https://t.co/G1xnf3Dwfl https://t.co/EOoqD6SV6t
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Mashup Score: 1Deformation of Aflibercept and Ranibizumab syringes cause variation in intravitreal injection volume and risks retinal tear formation - 2 year(s) ago
Aflibercept, ranibizumab and to a lesser extent, TB syringes, possess stoppers which can readily deform to allow excess volume to be delivered. If this excess force is released within the eye, vitreous may become incarcerated.
Source: Ophthalmology ScienceCategories: Latest Headlines, OphthalmologyTweet-
Researchers show that intravitreal injection volume administration varies significantly due to syringe stopper deformation when even slight amounts of excess force is applied. https://t.co/0LonaZaQfN https://t.co/zjCFLVomIO
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Novel drug delivery, aerosolized methotrexate, reduces proliferative vitreoretinopathy in a preclinical, large animal model https://t.co/D4qaJ5CqbG https://t.co/wkBAdJTTFZ