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Mashup Score: 0
The availability of fresh frozen (FF) tissue is a barrier for implementing RNA sequencing (RNA-seq) in the clinic. The majority of clinical samples are stored as formalin-fixed, paraffin-embedded (FFPE) tissues. Exome capture platforms have been developed for RNA-seq from FFPE samples. However, these methods have not been systematically compared. We performed transcriptomic analysis of 32 FFPE…
Source: npj Genomic MedicineCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 12
The availability of fresh frozen (FF) tissue is a barrier for implementing RNA sequencing (RNA-seq) in the clinic. The majority of clinical samples are stored as formalin-fixed, paraffin-embedded (FFPE) tissues. Exome capture platforms have been developed for RNA-seq from FFPE samples. However, these methods have not been systematically compared. We performed transcriptomic analysis of 32 FFPE…
Source: npj Genomic MedicineCategories: Latest Headlines, Oncologists2Tweet-
RT @FaltasLab: Excited to share our new paper https://t.co/kEV6qAQp8w @Kyrillus2 @iRonB25 @davidwilkes1965 @PrincescaD @ElementoLab A. Alon…
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Mashup Score: 8
The availability of fresh frozen (FF) tissue is a barrier for implementing RNA sequencing (RNA-seq) in the clinic. The majority of clinical samples are stored as formalin-fixed, paraffin-embedded (FFPE) tissues. Exome capture platforms have been developed for RNA-seq from FFPE samples. However, these methods have not been systematically compared. We performed transcriptomic analysis of 32 FFPE…
Source: npj Genomic MedicineCategories: Latest Headlines, Oncologists1Tweet-
RT @FaltasLab: Excited to share our new paper https://t.co/kEV6qAQp8w @Kyrillus2 @iRonB25 @davidwilkes1965 @PrincescaD @ElementoLab A. Alon…
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Mashup Score: 4
The availability of fresh frozen (FF) tissue is a barrier for implementing RNA sequencing (RNA-seq) in the clinic. The majority of clinical samples are stored as formalin-fixed, paraffin-embedded (FFPE) tissues. Exome capture platforms have been developed for RNA-seq from FFPE samples. However, these methods have not been systematically compared. We performed transcriptomic analysis of 32 FFPE…
Source: npj Genomic MedicineCategories: Latest Headlines, UrologyTweet-
RT @FaltasLab: Excited to share our new paper https://t.co/kEV6qAQp8w @Kyrillus2 @iRonB25 @davidwilkes1965 @PrincescaD @ElementoLab A. Alon…
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Mashup Score: 2
The availability of fresh frozen (FF) tissue is a barrier for implementing RNA sequencing (RNA-seq) in the clinic. The majority of clinical samples are stored as formalin-fixed, paraffin-embedded (FFPE) tissues. Exome capture platforms have been developed for RNA-seq from FFPE samples. However, these methods have not been systematically compared. We performed transcriptomic analysis of 32 FFPE…
Source: npj Genomic MedicineCategories: Hem/Oncs, Latest HeadlinesTweet-
Excited to share our new paper https://t.co/kEV6qAQp8w @Kyrillus2 @iRonB25 @davidwilkes1965 @PrincescaD @ElementoLab A. Alonso @asbonerw and others. https://t.co/mzQGeblyja
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Mashup Score: 3Non-secretory multiple myeloma with unusual TFG-ALK fusion showed dramatic response to ALK inhibition - 3 year(s) ago
Non-secretory multiple myeloma (NSMM) constitutes a distinct entity of multiple myeloma characterized by the absence of detectable monoclonal protein and rarely an absence of free light chains in the serum and urine. Given its rarity, the genomic landscape, clinical course, and prognosis of NSSM are not well characterized. Here, we report a case of a patient with relapsed and refractory NSMM with…
Source: npj Genomic MedicineCategories: Hem/Oncs, Latest HeadlinesTweet-
Non-secretory multiple myeloma [NSMM] with unusual TFG-ALK fusion showed dramatic response to ALK inhibition [Mar 17, 2021] @ashiq_masood et al. @Nature_NPJ Genomic Medicine https://t.co/VwxAWNpjkA #mmsm #PrecisionMedicine #openaccess https://t.co/91TG86V9ZI
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Mashup Score: 3Non-secretory multiple myeloma with unusual TFG-ALK fusion showed dramatic response to ALK inhibition - 3 year(s) ago
Non-secretory multiple myeloma (NSMM) constitutes a distinct entity of multiple myeloma characterized by the absence of detectable monoclonal protein and rarely an absence of free light chains in the serum and urine. Given its rarity, the genomic landscape, clinical course, and prognosis of NSSM are not well characterized. Here, we report a case of a patient with relapsed and refractory NSMM with…
Source: npj Genomic MedicineCategories: Hem/Oncs, Latest HeadlinesTweet-
Non-secretory multiple myeloma [NSMM] with unusual TFG-ALK fusion showed dramatic response to ALK inhibition [Mar 17, 2021] @ashiq_masood et al. @Nature_NPJ Genomic Medicine https://t.co/VwxAWNpjkA #mmsm #PrecisionMedicine #openaccess
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Mashup Score: 2Non-secretory multiple myeloma with unusual TFG-ALK fusion showed dramatic response to ALK inhibition - 3 year(s) ago
Non-secretory multiple myeloma (NSMM) constitutes a distinct entity of multiple myeloma characterized by the absence of detectable monoclonal protein and rarely an absence of free light chains in the serum and urine. Given its rarity, the genomic landscape, clinical course, and prognosis of NSSM are not well characterized. Here, we report a case of a patient with relapsed and refractory NSMM with…
Source: npj Genomic MedicineCategories: Hem/Oncs, Latest HeadlinesTweet-
Non-secretory multiple myeloma [NSMM] with unusual TFG-ALK fusion showed dramatic response to ALK inhibition [Mar 17, 2021] @ashiq_masood et al. @Nature_NPJ Genomic Medicine https://t.co/VwxAWNpjkA #mmsm #PrecisionMedicine #openaccess
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Mashup Score: 0Non-secretory multiple myeloma with unusual TFG-ALK fusion showed dramatic response to ALK inhibition - 3 year(s) ago
Non-secretory multiple myeloma (NSMM) constitutes a distinct entity of multiple myeloma characterized by the absence of detectable monoclonal protein and rarely an absence of free light chains in the serum and urine. Given its rarity, the genomic landscape, clinical course, and prognosis of NSSM are not well characterized. Here, we report a case of a patient with relapsed and refractory NSMM with…
Source: npj Genomic MedicineCategories: Hem/Oncs, Latest HeadlinesTweet-
Non-secretory multiple myeloma [NSMM] with unusual TFG-ALK fusion showed dramatic response to ALK inhibition [Mar 17, 2021] @ashiq_masood et al. @Nature_NPJ Genomic Medicine https://t.co/VwxAWNpjkA #mmsm #PrecisionMedicine #openaccess https://t.co/arrBRlxjTX
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Mashup Score: 17Non-secretory multiple myeloma with unusual TFG-ALK fusion showed dramatic response to ALK inhibition - 3 year(s) ago
Non-secretory multiple myeloma (NSMM) constitutes a distinct entity of multiple myeloma characterized by the absence of detectable monoclonal protein and rarely an absence of free light chains in the serum and urine. Given its rarity, the genomic landscape, clinical course, and prognosis of NSSM are not well characterized. Here, we report a case of a patient with relapsed and refractory NSMM with…
Source: npj Genomic MedicineCategories: Hem/Oncs, Latest HeadlinesTweet-
Can you say personalized cancer therapy? Non-secretory multiple myeloma with unusual TFG-ALK fusion showed dramatic response to ALK inhibition | npj Genomic Medicine: https://t.co/XH9KFAONsc
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We recently showed that we could determine molecular subtypes using exome capture RNA-seq from Formalin Fixed Paraffin Embedded tumors (FFPE) https://t.co/kEV6qAQp8w This and other RNA expression-based technologies can be used as biomarkers for subtype-directed therapy trials.